mitochochria

  1. SNT Gatchaman

    Preprint The Role of SARS-CoV-2 Nucleocapsid Protein Persistence in Inducing Chronic Type I Interferon and Mitochondrial Dysfunction., 2025, Koenig et al.

    The Role of SARS-CoV-2 Nucleocapsid Protein Persistence in Inducing Chronic Type I Interferon and Mitochondrial Dysfunction. Andreas Koenig; Mohammad Quasem; Benjamin Zink; Doniyorbek Abdulla-Zoda; Priyanka Karunanidhi; Karolina Sienko; Christian Geier; Venkatesh Jayaraman; Rabia Malik; Kanza...
    • SNT Gatchaman
    • Thread
    • autoimmunity inteferon mavs mitochochria mitochondrial dysfunction systemic lupus erythematosus viral persistence
    • Replies: 0
    • Forum: Long Covid research
  2. forestglip

    [Transcriptome] in PBMCs of [LC] at a median follow-up of 28 months [...] reveals upregulation of JAK/STAT [...], 2025, Fineschi et al

    Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response Serena Fineschi, Joakim Klar, Juan Ramon Lopez Egido, Jens Schuster, Jonas Bergquist...
    • forestglip
    • Thread
    • annexin atp haemoglobin histone il-9 interferon jak-stat lactate long covid mitochochria mitochondrial dysfunction neutrophils oxidative phosphorylation ubiquitination
    • Replies: 19
    • Forum: Long Covid research
  3. SNT Gatchaman

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications, 2025, Semo+

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications Semo, Dilvin; Shomanova, Zornitsa; Sindermann, Jürgen; Mohr, Michael; Evers, Georg; Motloch, Lukas J.; Reinecke, Holger; Godfrey, Rinesh; Pistulli, Rudin Cardiovascular...
    • SNT Gatchaman
    • Thread
    • caspase caspase-1 glutathione grp78 il-1b immunoparalysis inflammasome mitochochria monocytes mtdna oxidative stress reactive oxygen species seahorse tlr-4 tlr-9
    • Replies: 2
    • Forum: Long Covid research
  4. SNT Gatchaman

    Review Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Syed, Karius, Wang, Hwang

    Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abu Mohammad Syed; Alexander K. Karius; Jin Ma; Ping-yuan Wang; Paul M. Hwang ME/CFS is a debilitating multisystem disorder of unclear etiology that affects many individuals worldwide. One of its hallmark symptoms...
    • SNT Gatchaman
    • Thread
    • actin atp eif2a endoplasmic reticulum er stress interferon jak-stat mitochochria mitochondrial dysfunction nf-κb wasf3
    • Replies: 15
    • Forum: ME/CFS research
  5. SNT Gatchaman

    Rhodoquinone carries electrons in the mammalian electron transport chain, 2025, Valeros et al.

    Rhodoquinone carries electrons in the mammalian electron transport chain Jonathan Valeros et 31 al. Ubiquinone (UQ), the only known electron carrier in the mammalian electron transport chain (ETC), preferentially delivers electrons to the terminal electron acceptor oxygen (O2). In hypoxia...
  6. SNT Gatchaman

    Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion … in space, 2025, Moreno-Villanueva+

    Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space Moreno-Villanueva, Maria; Jimenez-Chavez, Luis E.; Krieger, Stephanie; Ding, Liang-Hao; Zhang, Ye; Babiak-Vazquez, Adriana; Berres, Mark; Splinter...
  7. SNT Gatchaman

    Review A Comprehensive Review of the Contribution of Mitochondrial DNA Mutations and Dysfunction in Polycystic Ovary Syndrome, 2025, Kobayashi+

    A Comprehensive Review of the Contribution of Mitochondrial DNA Mutations and Dysfunction in Polycystic Ovary Syndrome, Supported by Secondary Database Analysis Kobayashi, Hiroshi; Matsubara, Sho; Yoshimoto, Chiharu; Shigetomi, Hiroshi; Imanaka, Shogo Polycystic ovary syndrome (PCOS) is a...
  8. Mij

    Muscle Mitochondrial Capacity Is Impaired Immediately Following Maximal Exercise, 2025, Dickinson et al

    Abstract Mitochondria are essential in supplying energy to skeletal muscle. Near-infrared spectroscopy (NIRS) was developed to noninvasively assess mitochondrial capacity (mV̇O2max) as a rate constant of metabolic recovery after exercise. Purpose This study measured the time course mV̇O2max...
  9. Yann04

    Thesis Bedside Monitoring of Mitochondrial Function in Post- COVID Patients, 2024, Behr

    (masters thesis) Background: Post-COVID (PC) is characterized by prolonged symptoms following a COVID-19 infection, with Post-Exertional Malaise (PEM) being a feature with a large negative impact on quality of life. Mitochondrial dysfunction has previously been related to PEM-related symtpoms...
  10. SNT Gatchaman

    Proteolethargy is a pathogenic mechanism in chronic disease, 2024, Dall’Agnese et al

    Proteolethargy is a pathogenic mechanism in chronic disease Alessandra Dall’Agnese; Ming M. Zheng; Shannon Moreno; Jesse M. Platt; An T. Hoang; Deepti Kannan; Giuseppe Dall’Agnese; Kalon J. Overholt; Ido Sagi; Nancy M. Hannett; Hailey Erb; Olivia Corradin; Arup K. Chakraborty; Tong Ihn Lee...
    • SNT Gatchaman
    • Thread
    • chronic illness cysteine cytoplasm endoplasmic reticulum enos er stress insulin receptor insulin resistance mitochochria protein mobility proteolethargy reactive oxygen species
    • Replies: 13
    • Forum: Other health news and research
  11. SNT Gatchaman

    Lipid storage myopathy associated with sertraline is an acquired mitochondrial disorder with respiratory chain deficiency, 2024, Hedberg-Oldfors+

    Lipid storage myopathy associated with sertraline treatment is an acquired mitochondrial disorder with respiratory chain deficiency Hedberg-Oldfors, Carola; Lindgren, Ulrika; Visuttijai, Kittichate; Shen, Yan; Ilinca, Andreea; Nordström, Sara; Lindberg, Christopher; Oldfors, Anders Lipid...
  12. SNT Gatchaman

    The metabolic and physiologic impairments underlying long COVID associated exercise intolerance, 2024, Leitner, Singh et al.

    The metabolic and physiologic impairments underlying long COVID associated exercise intolerance Brooks P. Leitner; Phillip Joseph; Andres Figueroa Quast; Maria Alejandra Ramirez; Paul M. Heerdt; Jose G. Villalobos; Inderjit Singh Data from invasive CPET (iCPET) revealed long COVID patients have...
  13. Mij

    The human heart shows signs of ageing after just a month in space

    Researchers sent engineered heart tissue to the International Space Station and measured how it faired. The study offers a useful means of identifying the molecular pathways behind the detrimental effects of spaceflight on the human heart, says Joseph Wu, a cardiologist at Stanford University...
  14. SNT Gatchaman

    A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria, 2024, Hernansanz-Agustín et al.

    A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria Pablo Hernansanz-Agustín; Carmen Morales-Vidal; Enrique Calvo; Paolo Natale; Yolanda Martí-Mateos; Sara Natalia Jaroszewicz; José Luis Cabrera-Alarcón; Rebeca Acín-Pérez; Iván López-Montero; Jesús Vázquez...
  15. Mij

    Cerebral blood flow alterations and host genetic association in individuals with long COVID: A transcriptomic-neuroimaging study, 2024, Yao Wang et al

    Abstract Neuroimaging studies have indicated that altered cerebral blood flow (CBF) was associated with the long-term symptoms of postacute sequelae of SARS-CoV-2 infection (PASC), also known as “long COVID”. COVID-19 and long COVID were found to be strongly associated with host gene expression...
    • Mij
    • Thread
    • cerebral blood flow mitochochria mri transcriptomics
    • Replies: 2
    • Forum: Long Covid research
  16. SNT Gatchaman

    Neuro-intestinal acetylcholine signalling regulates the mitochondrial stress response in Caenorhabditis elegans, 2024, Cornell+

    Neuro-intestinal acetylcholine signalling regulates the mitochondrial stress response in Caenorhabditis elegans Cornell, Rebecca; Cao, Wei; Harradine, Bernie; Godini, Rasoul; Handley, Ava; Pocock, Roger Neurons coordinate inter-tissue protein homeostasis to systemically manage cytotoxic stress...
  17. SNT Gatchaman

    Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes, 2024, Scheiblich et al.

    Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes Hannah Scheiblich; Frederik Eikens; Lena Wischhof; Sabine Opitz; Kay Jüngling; Csaba Cserép; Susanne V. Schmidt; Jessica Lambertz; Tracy Bellande; Balázs Pósfai; Charlotte Geck; Jasper...
  18. SNT Gatchaman

    Preprint ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism, 2024, Dematteis+

    ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism. Giulia Dematteis; Laura Tapella; Claudio Casali; Maria Talmon; Elisa Tonelli; Simone Reano; Adele Ariotti; Emanuela Pessolano; Mustyna Malecka; Gabriela Chrostek; Gabriele...
  19. SNT Gatchaman

    The germline coordinates mitokine signaling, 2024, Shen et al.

    The germline coordinates mitokine signaling Koning Shen; Jenni Durieux; Cesar G. Mena; Brant M. Webster; C. Kimberly Tsui; Hanlin Zhang; Larry Joe; Kristen M. Berendzen; Andrew Dillin The ability of mitochondria to coordinate stress responses across tissues is critical for health. In C...
  20. SNT Gatchaman

    The extracellular matrix integrates mitochondrial homeostasis, 2024, Zhang et al.

    The extracellular matrix integrates mitochondrial homeostasis Hanlin Zhang; C. Kimberly Tsui; Gilberto Garcia; Larry K. Joe; Haolun Wu; Ayane Maruichi; Wudi Fan; Sentibel Pandovski; Peter H. Yoon; Brant M. Webster; Jenni Durieux; Phillip A. Frankino; Ryo Higuchi-Sanabria; Andrew Dillin SUMMARY...
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