mitochondrial dna

  1. forestglip

    mtDNA deletion [...] with < 10 % heteroplasmy in muscle and isolated complex-V dysfunction misinterpreted as [CFS] over 21-years, 2025, Finsterer+

    mtDNA deletion m.8753_16566 with < 10 % heteroplasmy in muscle and isolated complex-V dysfunction misinterpreted as chronic fatigue syndrome over 21-years Josef Finsterer, Ana C. Fiorini, Fulvio A. Scorza, Carla A. Scorza [No abstract] Link | PDF (Clinics) [Open Access]
    • forestglip
    • Thread
    • complex v me/cfs mitochondrial dna mitochondrial dysfunction
    • Replies: 12
    • Forum: ME/CFS research
  2. ME/CFS Skeptic

    Mitochondrial DNA variants correlate with symptoms in ME/CFS 2016 Billing-Ross et al.

    Paper from 2016 by the Hanson group. I wanted to post it here because it had a large sample size (large for ME/CFS research, probably small for genetics research). Abstract Background: Mitochondrial dysfunction has been hypothesized to occur in Myalgic Encephalomyelitis/Chronic Fatigue...
  3. LarsSG

    Is ME more heritable on the mother's side?

    Are mothers with ME more likely to have children with ME than fathers with ME are? I've always wondered about this, partly because it is true in my own family, and have seen others suggest it might be true (most recently Fereshteh Jahaniani in the NIH genetics webinar), but I can't seem to find...
  4. SNT Gatchaman

    Mitochondrial Dysfunction: A Prelude to Neuropathogenesis of SARS-CoV‐2, 2022, Pliss et al

    Mitochondrial Dysfunction: A Prelude to Neuropathogenesis of SARS-CoV‐2 Artem Pliss, Andrey N. Kuzmin, Paras N. Prasad, Supriya D. Mahajan The SARS-CoV-2 virus is notorious for its neuroinvasive capability, causing multiple neurological conditions. The neuropathology of SARS-CoV-2 is...
    • SNT Gatchaman
    • Thread
    • covid-19 microglia mitochondria mitochondrial dna reactive oxygen species spike protein
    • Replies: 2
    • Forum: Long Covid research
  5. John Mac

    Exosome-associated Mitochondrial DNA is Elevated in Patients with ME/CFS and Stimulates Human Cultured Microglia to Secrete IL-1β, 2021, Theoharides

    https://www.researchsquare.com/article/rs-154011/v1
    • John Mac
    • Thread
    • 2021 exercise me/cfs mitochondrial dna natelson paper pem theoharides
    • Replies: 3
    • Forum: ME/CFS research
  6. Andy

    Article: The role of mitochondria in ME/CFS: a perspective, 2019, Tomas and Elson

    Paywalled at https://www.tandfonline.com/doi/full/10.1080/21641846.2019.1580855 Sci Hub, http://sci-hub.tw/https://www.tandfonline.com/doi/full/10.1080/21641846.2019.1580855
    • Andy
    • Thread
    • 2019 bioenergetics elson me/cfs mitochondria mitochondrial dna tomas
    • Replies: 12
    • Forum: ME/CFS research news
  7. Andy

    Not Your Mom’s Genes: Mitochondrial DNA Can Come from Dad

    https://www.pbs.org/wgbh/nova/article/dads-mitochondrial-dna/
  8. Andy

    Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress, 2018, Lee et al

    Paywalled at https://www.cell.com/cell-metabolism/abstract/S1550-4131(18)30390-5 Article on the study https://news.usc.edu/145046/mitochondrial-dna-nuclear-dna-work-together-usc-study/
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