mitochondrial function

  1. Nightsong

    Preprint ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion, 2025, Prusty et al

    Abstract: Autoimmunity is a key clinical feature in both post-infectious Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of COVID (PASC). Passive transfer of immunoglobulins from patients' sera into mice induces some clinical features of PASC. IgG-induced...
    • Nightsong
    • Thread
    • bhupesh prusty igg immunoglobulin iron kallikreins me/cfs mitochondrial function proteomics scheibenbogen transferrin vwf
    • Replies: 23
    • Forum: ME/CFS research
  2. Hutan

    Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine, 2020, Dijk et al

    https://www.nature.com/articles/s41598-020-61381-9#Fig1 Doxycycline has anti-tumour effects in a range of tumour systems. The aims of this study were to define the role mitochondria play in this process and examine the potential of doxycycline in combination with gemcitabine. We studied the...
  3. Hoopoe

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    The pre-publication thread has been merged with the thread on the paper. Link to paper's abstract here...
    • Hoopoe
    • Thread
    • bip endoplasmic reticulum er stress exercise intolerance grp78 mitochondrial function mouse model muscle biopsy p53 perk salubrinal seahorse study idea wasf3 wave3
    • Replies: 253
    • Forum: ME/CFS research
  4. Andy

    Time dependent changes in the bioenergetics of PBMCs: processing time, collection tubes and cryopreservation effects 2023 Werner et al

    Full title: Time dependent changes in the bioenergetics of peripheral blood mononuclear cells: processing time, collection tubes and cryopreservation effects Objectives: Bioenergetic measurements in peripheral blood mononuclear cells (PBMCs) using high-throughput respirometry is a promising...
  5. Sly Saint

    Measuring mitochondrial function

    Copied post this might be of interest from 2007 Assay: Measurement of Mitochondrial Function https://www.genengnews.com/magazine/80/assay-measurement-of-mitochondrial-function/
  6. leokitten

    The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity. Wild et al. Int J Mol Sci 2020

    Full title: The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism Another paper examining virus-induced mitochondrial fragmentation/fission in this case by HCMV and effects of an artesunate-derived...
    • leokitten
    • Thread
    • antiviral drugs artemisinin cytomegalovirus mitochondria mitochondrial architecture mitochondrial fragmentation mitochondrial function
    • Replies: 0
    • Forum: Other health news and research
  7. Andy

    Mitochondria Play an Unexpected Role in Killing Bacteria

    https://www.the-scientist.com/the-literature/mitochondria-play-an-unexpected-role-in-killing-bacteria-65246
    • Andy
    • Thread
    • immunology macrophages mitochondria mitochondrial function pathogens reactive oxygen species white blood cells
    • Replies: 6
    • Forum: Other health news and research
  8. Jenny TipsforME

    Acupuncture, metabolomics and mitochondrial function

    I got this in my inbox today and it piqued my cognitively foggy interest for a couple of reasons. NB these posts move onto considering a study on metabolomics and the credibility of acupuncture (the thread isn’t specific to this study). First of all I want to comment that I’m very sceptical of...
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