muscle fatigability

  1. jnmaciuch

    Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome, 2015, Brown+

    Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome (2015) Audrey E. Brown, David E. Jones, Mark Walker, Julia L. Newton Background Post exertional muscle fatigue is a key feature in Chronic Fatigue Syndrome...
  2. InitialConditions

    Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle‑serving nerves and spinal cord, 2025, Drosen et al.

    Abstract Chronic muscle fatigue is a condition characterized by debilitating muscle weakness and pain. Based on our recent finding to study the potential effect of mTOR on ATG13 inactivation in chronic muscle fatigue, we report that biweekly oral administration with MHY1485, a potent inducer of...
  3. Kalliope

    Review Key Pathophysiological Role of Skeletal Muscle Disturbance in Post COVID and ME/CFS: Accumulated Evidence, Scheibenbogen et al, 2024

    ABSTRACT Background Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In a 2021 review article on the pathophysiology of ME/CFS, we postulated that hypoperfusion and ischemia can result in...
  4. SNT Gatchaman

    Ebbing Strength, Fading Power: Unveiling the Impact of Persistent Fatigue on Muscle Performance in COVID-19 Survivors, 2024, Kowal et al.

    Ebbing Strength, Fading Power: Unveiling the Impact of Persistent Fatigue on Muscle Performance in COVID-19 Survivors Kowal, Mateusz; Morgiel, Ewa; Winiarski, Sławomir; Dymarek, Robert; Bajer, Weronika; Madej, Marta; Sebastian, Agata; Madziarski, Marcin; Wedel, Nicole; Proc, Krzysztof...
  5. SNT Gatchaman

    Thesis Eccentrically Induced Skeletal Muscle Damage in Patients With Chronic Fatigue Syndrome CFS, With Reference to Overtrained Athletes, 1995, Wright

    Eccentrically Induced Skeletal Muscle Damage in Patients With Chronic Fatigue Syndrome CFS, With Reference to Overtrained Athletes David L. Wright Bachelor of Applied Science (Sports Science) with Honours: Faculty of Science and Technology, Edith Cowan University Chronic fatigue syndrome (CFS)...
  6. Andy

    Molecular Mechanisms of Muscle Fatigue, 2021, Constantin-Teodosiu and Constantin

    Abstract Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of tiredness or lack of energy. The leading causes of short-lasting fatigue are related to overtraining...
  7. M

    Symptomatic Treatment: Huperzine A/B

    The following is only meant for people with neurological ME as defined by the Charitè CFS/ME center in 10.1016/j.bbi.2015.09.013. They define the disease's mechanism to be mediated by adrenergic- and muscarinergic-binding subtypes of acetylcholine-receptor antibodies. Acetylcholine-receptor...
  8. Snow Leopard

    Association between dystrophin, focal adhesion and muscle fatigability - discussion thread

    (I apologise if this seems to be a little obscure). Animal models suggest a relationship between dystrophin and muscle fibre fatiguability. Hyperhomocysteinemia associated skeletal muscle weakness involves mitochondrial dysfunction and epigenetic modifications...
  9. adambeyoncelowe

    Myalgic Encephalomyelitis or What? The International Consensus Criteria (Frank Twisk, 2019)

    Abstract published today: Abstract Myalgic encephalomyelitis (ME) is a neuromuscular disease with two distinctive types of symptoms (muscle fatigability or prolonged muscle weakness after minor exertion and symptoms related to neurological disturbance, especially of sensory, cognitive, and...
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