Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome (2015)
Audrey E. Brown, David E. Jones, Mark Walker, Julia L. Newton
Background
Post exertional muscle fatigue is a key feature in Chronic Fatigue Syndrome...
Abstract
Chronic muscle fatigue is a condition characterized by debilitating muscle weakness and pain. Based on our recent finding to study the potential effect of mTOR on ATG13 inactivation in chronic muscle fatigue, we report that biweekly oral administration with MHY1485, a potent inducer of...
ABSTRACT
Background
Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In a 2021 review article on the pathophysiology of ME/CFS, we postulated that hypoperfusion and ischemia can result in...
Eccentrically Induced Skeletal Muscle Damage in Patients With Chronic Fatigue Syndrome CFS, With Reference to Overtrained Athletes
David L. Wright
Bachelor of Applied Science (Sports Science) with Honours: Faculty of Science and Technology, Edith Cowan University
Chronic fatigue syndrome (CFS)...
Abstract
Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of tiredness or lack of energy. The leading causes of short-lasting fatigue are related to overtraining...
The following is only meant for people with neurological ME as defined by the Charitè CFS/ME center in 10.1016/j.bbi.2015.09.013. They define the disease's mechanism to be mediated by adrenergic- and muscarinergic-binding subtypes of acetylcholine-receptor antibodies. Acetylcholine-receptor...
(I apologise if this seems to be a little obscure).
Animal models suggest a relationship between dystrophin and muscle fibre fatiguability.
Hyperhomocysteinemia associated skeletal muscle weakness involves mitochondrial dysfunction and epigenetic modifications...
Abstract published today:
Abstract
Myalgic encephalomyelitis (ME) is a neuromuscular disease with two distinctive types of symptoms (muscle fatigability or prolonged muscle weakness after minor exertion and symptoms related to neurological disturbance, especially of sensory, cognitive, and...
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