neurology

  1. Sly Saint

    Article: Doctors say a silent 'mini-stroke' may explain your constant fatigue

    Doctors say a silent 'mini-stroke' may explain your constant fatigue see press release American Academy of Neurology: Neurology Resources | AAN research paper: Long-Term Fatigue Following Transient Ischemic Attack | Neurology
  2. AR561

    Positive signs for FND: Looking for Criticism

    Hello. I am new to here and have an interest in critiques of Functional Neurological Disorder. I knew that three "positive" rule-in signs were tremor entrapments, Hoover's sign, and psychogenic seizures, but I also found a table that listed positive signs you will see in the table linked below...
  3. SNT Gatchaman

    Emerging Subspecialties in Neurology: Women’s Neurology, 2024, Thornton et al

    Emerging Subspecialties in Neurology: Women’s Neurology Hayley F. Thornton,, Sara C. LaHue, Riley Bove, Janet Waters, Mary A. O’Neal, Esther Bui The influence of sex and gender on neurologic disease has become increasingly recognized in science and medicine. This is evident across a woman’s...
  4. cassava7

    Against cortical reorganisation, Makin and Krakauer, 2023 (brain rewiring)

    Tamar R Makin MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom John W Krakauer Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States Department of Neurology, Johns Hopkins University School of Medicine...
  5. C

    How I rewired my brain in six weeks

    BBC How I rewired my brain in six weeks There is growing evidence that simple, everyday changes to our lives can alter our brains and change how they work. Melissa Hogenboom put herself into a scanner to find out. "It's surprisingly hard to think of nothing at all", is one of my first...
  6. rvallee

    SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity, 2023, Hilliard et al

    SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity https://www.science.org/doi/10.1126/sciadv.adg2248 Abstract Numerous viruses use specialized surface molecules called fusogens to enter host cells. Many of these viruses, including the...
  7. Wyva

    American Academy of Neurology - Annual Meeting April 22-27 2023

    Here is the link to the event on the website of the AAN. And here you can check out the abstracts of the topics that are going to be presented. I typed in ME/CFS keywords but couldn't find anything, however, the word covid brings up plenty of abstracts. I haven't really gone through all of...
  8. Wyva

    Impact of the COVID-19 pandemic on clinical autonomic practice in Europe A survey of the European Academy of Neurology and(...), 2023, Fanciulli et al

    Full title: Impact of the COVID-19 pandemic on clinical autonomic practice in Europe A survey of the European Academy of Neurology (EAN) and the European Federation of Autonomic Societies (EFAS) Abstract Objective To investigate the impact of the coronavirus-disease-2019 (COVID-19) pandemic...
  9. C

    The pernicious danger of cortical brain maps, 2022, Benjamin Yost Hayden

    Pre Print: The pernicious danger of cortical brain maps Benjamin Yost Hayden The parcellation of the primate cerebral cortex into numbered regions, based on cytoarchitecture, began with the pioneering research of neuroanatomist Kobrinian Brodmann. While the borders between regions have...
  10. L

    Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS, 2021, Li et al

    Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS Lucia M Li, NIHR clinical lecturer,A Michael D Dilley, consultant neuropsychiatrist,B Alan Carson, consultant neuropsychiatrist and honorary professor,C Jaq Twelftree, AHP consultant in...
  11. C

    Diagnostic approach in adult-onset neurometabolic diseases, 2022, Fernández-Eulate et al

    Diagnostic approach in adult-onset neurometabolic diseases Gorka Fernández-Eulate, Christophe Carreau, Jean-François Benoist, Foudil Lamari, Benoit Rucheton, Natalia Shor, Yann Nadjar Abstract Neurometabolic diseases are a group of individually rare but numerous and heterogeneous genetic...
  12. Arvo

    SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients, 2023, Charvet et al.

    :emoji_warning: At this point it's still a preprint. Abstract: As most of you know, in the 80s researchers were excited about several (and separate) finds of retroviral activity in what we now call ME/CFS patients. The main researcher was Elaine DeFreitas, whose finds got dismissed by UK...
  13. C

    The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure, 2022, Renz-Polster et al

    https://osf.io/ef3n4/ The newsbrief posting reminded me that this paper wasn't mentioned. I think it may be a pretty important hypothesis for ME's root cause. It fits what I believe is the root cause of ME: that neuroglia are involved. I'm not sure whether there are any ME symptoms that...
  14. Andy

    Using the Biopsychosocial Model to Guide Patient-Centered Neurological Treatments, 2022, Saxena, Perez et al

    Abstract The biopsychosocial model was defined by George L. Engel to propose a holistic approach to patient care. Through this model, physicians can understand patients in their context to aid the development of tailored, individualized treatment plans that consider relevant biological...
  15. Dolphin

    Investigating the neural underpinnings of Chronic Fatigue: A multi-modal approach, 2021, Rayhan (PhD thesis)

    Source: Howard University Date: April 16, 2021 URL: https://www.proquest.com/openview/c0a823ec519e5e6acdd89c29ff4a4b2a/1 Investigating the neural underpinnings of Chronic Fatigue: A multi-modal approach ---------------------------------------------------------- Rakib U. Rayhan -...
  16. rvallee

    Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling, Bisht et al, 2021

    In mice. https://www.biorxiv.org/content/10.1101/2021.08.02.454769v1 TL;DR: microglia can influence cerebral vasculature. (Paragraphs mine for legibility) Microglia are brain-resident immune cells with a repertoire of functions in the developing, mature and pathological brain. Their...
  17. rvallee

    Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T cell interactions, 2021

    Performed detailed molecular and spatial analysis of the COVID-19 brain immune response Pathognomonic microglial nodules and T cell infiltration are present in COVID-19 brains Altered microglia-T cell interactions correlate with systemic measures of inflammation Vascular leakage is linked with...
  18. rvallee

    COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital, 2021, Thakur et al

    (Line breaks mine for legibility) Many patients with SARS-CoV-2 infection develop neurological signs and symptoms, though, to date, little evidence exists that primary infection of the brain is a significant contributing factor. We present the clinical, neuropathological, and molecular findings...
  19. rvallee

    Challenges in defining [LC]: Striking differences across literature, Electronic Health Records, and patient-reported information, 2021, Rando et al

    Since late 2019, the novel coronavirus SARS-CoV-2 has introduced a wide array of health challenges globally. In addition to a complex acute presentation that can affect multiple organ systems, increasing evidence points to long-term sequelae being common and impactful. As the worldwide...
  20. rvallee

    Functional and microstructural brain abnormalities, fatigue, and cognitive dysfunction after mild COVID-19, 2021, Silva et al

    (Paragraphed for clarity) Although post-acute cognitive dysfunction and neuroimaging abnormalities have been reported after hospital discharge in patients recovered from COVID-19, little is known about persistent, long-term alterations in people without hospitalization. We conducted a...
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