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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0315486 Michael R. Lawrence, Judith E. Arnetz , Scott E. Counts, Aiesha Ahmed, Bengt B. Arnetz https://doi.org/10.1371/journal.pone.0315486 Abstract Substantial numbers of individuals who contract COVID-19 experience...

Plasma neurofilament light chain in fibromyalgia: A case control study exploring correlation with clinical and cognitive features Maddalena Ruggieri, Giulia Paparella, Livio Clemente, Giuseppe Libro, Concetta Domenica Gargano, Marina de Tommaso Background Plasma neurofilament light chain...

Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: the ADVANCE study Neil SN Graham; Grace Blissitt; Karl Zimmerman; Lydia Orton; Daniel Friedland; Emma Coady; Rhiannon Laban; Elena Veleva; Amanda J Heslegrave; Henrik Zetterberg; Susie...

Abstract Infections have been associated with the incidence of Alzheimer disease and related dementias, but the mechanisms responsible for these associations remain unclear. Using a multicohort approach, we found that influenza, viral, respiratory, and skin and subcutaneous infections were...

Full title: Plasma Neurofilament Light Chain: A Potential Biomarker for Neurological Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disorder characterized by heterogeneous symptoms, which lack...

Clinical and Diagnostic Features of Post-Acute COVID-19 Vaccination Syndrome (PACVS) Anna Katharina Mundorf, Amelie Semmler, Harald Heidecke, Matthias Schott, Falk Steffen, Stefan Bittner, Karl J. Lackner, Karin Schulze-Bosse, Marc Pawlitzki, Sven Guenther Meuth, Frank Klawonn, Jana Ruhrländer...

Transfer of IgG from Long COVID patients induces symptomology in mice Vidarsson, G., Bos, A., van Vugt, M., den Dunnen, J., Wiersinga, W. J., Wust, R., Amsterdam UMC COVID-19 biobank,, Versteeg, S., Silva Santos Ribeiro, P., Willemen, H., Geyer, C. E., Larsen, M. D., Prado, J., Charlton, B...

Neurological involvement among non-hospitalized adolescents and young adults 6 months after acute COVID-19 Havdal, Lise Beier; Selvakumar, Joel; Lund Berven, Lise; Stiansen-Sonerud, Tonje; Zetterberg, Henrik; Blennow, Kaj; Holmøy, Trygve; Wyller, Vegard The post-COVID-19 condition (PCC) is...

Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury 536 authors A proportion of patients infected with severe acute respiratory syndrome coronavirus 2 experience a range of neuropsychiatric symptoms months after infection, including cognitive...

Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses Abstract To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and...

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome Maria Díez-Cirarda; Miguel Yus-Fuertes; Rafael Sanchez-Sanchez; Javier J. Gonzalez-Rosa; Gabriel Gonzalez-Escamilla; Lidia Gil-Martínez; Cristina Delgado-Alonso...

Link to published version: https://www.s4me.info/threads/long-covid-plasma-levels-of-neurofilament-light-chain-in-mild-covid-19-patients-with-neurocognitive-symptoms-2023-gutman-et-al.33354/#post-529159 *** Preprint It is well known the potential of severe acute respiratory coronavirus type 2...

Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Post acute Sequelae of SARS-CoV-2 Infection, 2022, Michael J. Peluso et al Abstract Background and Objectives The biologic mechanisms underlying neurologic post acute sequelae of severe acute...

A drug company called Ashvattha Therapeutics is working on a new drug candidate for long Covid, OP-101. Link: Ashvattha previews plans for long Covid trial in mid-2023 Key takeaways: OP-101 was originally developed for neurodegenerative disease They're discussing their plans with the FDA so...

Patients with coronavirus disease 2019 (COVID-19) frequently develop acute encephalopathy and encephalitis, but whether these complications are the result from viral-induced cytokine storm syndrome or anti-neural autoimmunity is still unclear. In this study, we aimed to evaluate the diagnostic...

Abstract The identification of intestinal dysbiosis in patients with neurological and psychiatric disorders has highlighted the importance of gut-brain communication and yet, the question regarding the identity of the components responsible for this cross talk remains open. We previously...

Abstract SARS-CoV-2 survivors may report persistent symptoms that resemble myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We explored (a) ME/CFS-like symptom prevalence and (b) whether axonal, inflammatory, and/or lung changes may contribute to ME/CFS-like symptoms in SARS-CoV-2...

https://www.mdpi.com/2073-4409/10/2/386 Abstract As the SARS-CoV-2 pandemic continues, reports have demonstrated neurologic sequelae following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are unknown and need to be identified. Plasma from 24 individuals recovering...

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