nsaids

  1. Sly Saint

    Article: Pharmacist warns against taking common drug that can 'harm hearing'

    https://www.express.co.uk/life-style/health/2113729/pharmacist-warns-against-taking-common
  2. E

    Protocol Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2 (PASC) - Bateman Horne Center - RCT

    Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2 (PASC) A new RCT has been uploaded to clinicaltrials.gov. The study is sponsored and led by the Bateman Horne Center under the leadership of Lucinda Bateman. Brief Summary: To explore the safety and efficacy of daily doses of...
  3. cassava7

    Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of [OTC] and prescription NSAIDs, Eisenstein.., 2022

    Highlights A subset of nonsteroidal anti-inflammatory drugs (NSAIDs) activates NRF2 C151 of the chaperone protein KEAP1 is necessary for NRF2 activation by indomethacin Indomethacin reduces inflammation in endotoxemia and gout models dependent on NRF2 Summary Nonsteroidal...
  4. Trish

    Acute inflammatory response via neutrophil activation protects against the development of chronic pain, 2022, Parisien et al.

    https://www.science.org/doi/10.1126/scitranslmed.abj9954 Beneficial inflammation Chronic pain can develop from an acute pain state. The mechanisms mediating the transition from acute to chronic pain remain to be elucidated. Here, Parisien et al. focused on the immune system using samples from...
  5. Hutan

    NSAIDS (Nonsteroidal Anti-Inflammatory Drugs), e.g. Ibuprofen, Aspirin

    A few years ago, on the basis of my symptom tracking, I convinced my GP that ibuprofen was making a difference and she agreed to prescribe Mobic (meloxicam) as a trial (or perhaps she humoured me). It didn't work. My understanding is that Mobic is a COX-2 inhibitor whereas ibuprofen is both a...
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