SARS-CoV-2 S1 protein induces IgG-mediated platelet activation and is prevented by 1.8-cineole
Petry; Shoykhet; Weiser; Griesbaum; Bashiri Dezfouli; Verschoor; Wollenberg
COVID-19 patients face an increased risk of thromboembolic complications, yet the exact pathophysiological role of platelets...
Abstract
Background: Neuropsychiatric symptoms are prominent and can have a substantial functional impact in many people with Long COVID (LC). The underlying pathophysiology of neuropsychiatric LC (N-LC) is unknown.
Methods: 28 individuals with acute COVID-19 (AC), 50 N-LC (new or worsening...
Abstract
We investigated if children with Long Covid (n=14) have activated platelets compared with healthy controls (n=14). Platelet activation and secretion markers were investigated by flow cytometry using MoAbs directed against P-selectin, CD63, and PAC-1 in quiescent platelets and in...
Preprint
Blood-brain barrier disruption in Long COVID-associated cognitive impairment
Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell
Vascular disruption has been...
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