pericytes

  1. Mij

    SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells . . . smooth muscle cells as key mediators vascular pathology, 2024

    Full Title: SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection, 2024, Alexsia Richards et al Abstract Although respiratory symptoms are the most prevalent disease manifestation of...
  2. SNT Gatchaman

    Astrocytic mitochondrial transfer to brain endothelial cells and pericytes in vivo increases with aging, 2024, Velmurugan+

    Astrocytic mitochondrial transfer to brain endothelial cells and pericytes in vivo increases with aging Gopal V Velmurugan; Hemendra J Vekaria; Samir P Patel; Patrick G Sullivan; W Brad Hubbard Intercellular mitochondrial transfer (IMT) is an intriguing biological phenomenon where mitochondria...
  3. E

    Preprint SARS-CoV-2 RNA Persists in the Central Nervous System of Non-Human Primates Despite Clinical Recovery, 2023, Booze et al

    SARS-CoV-2 RNA Persists in the Central Nervous System of Non-Human Primates Despite Clinical Recovery Abstract Adverse neurological and psychiatric outcomes, collectively termed the post-acute sequelae of SARS-CoV-2 infection (PASC), persist in adults clinically recovered from COVID-19...
  4. SNT Gatchaman

    Neurovascular Coupling

    Neurovascular coupling is the concept that in the CNS, organ function is tightly associated with blood flow, moreso than in other organs. Theoretical background and latest thinking — From the introduction in The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in...
  5. Andy

    The post-arteriole transitional zone: a specialized capillary region that regulates blood flow within the CNS microvasculature 2023 Mughal et al

    Abstract The brain is an energy hog, consuming available energy supplies at a rate out of all proportion to its relatively small size. This outsized demand, largely reflecting the unique computational activity of the brain, is met by an ensemble of neurovascular coupling mechanisms that link...
  6. Andy

    Ebola virus disrupts the inner blood-retinal barrier by induction of vascular endothelial growth factor in pericytes 2023 Gao et al

    Abstract Ebola virus (EBOV) causes severe hemorrhagic fever in humans with high mortality. In Ebola virus disease (EVD) survivors, EBOV persistence in the eyes may break through the inner blood–retinal barrier (iBRB), leading to ocular complications and EVD recurrence. However, the mechanism by...
  7. Andy

    The Emerging Role of Pericyte-Derived Extracellular Vesicles in Vascular and Neurological Health 2022 Sharma et al

    Abstract Pericytes (PCs), as a central component of the neurovascular unit, contribute to the regenerative potential of the central nervous system (CNS) and peripheral nervous system (PNS) by virtue of their role in blood flow regulation, angiogenesis, maintenance of the BBB, neurogenesis, and...
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