pf4

  1. SNT Gatchaman

    Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment, 2024, Greene et al

    Preprint Blood-brain barrier disruption in Long COVID-associated cognitive impairment Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O'Keeffe, Lilia Zaporojan, Emma Connolly, Cliona Ni Cheallaigh, Niall Conlon, Colin Doherty, Matthew Campbell Vascular disruption has been...
    • SNT Gatchaman
    • Thread
    • blood brain barrier brain imaging coagulation csf dce-mri endothelial gfap icam-1 inflammation long covid long covid clinic mri p-selectin pf4 platelets s100 scam-1 spike protein t cells tgf-beta tnf
    • Replies: 44
    • Forum: Long Covid research
  2. Andy

    Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [11C]PBR28 PET correlates with vascular disease measures, 2023, VanElzakker

    Published version linked in this later post here Preprint Abstract The COVID-19 pandemic caused by SARS-CoV-2 has triggered a consequential public health crisis of post-acute sequelae of COVID-19 (PASC), sometimes referred to as long COVID. The mechanisms of the heterogeneous persistent...
    • Andy
    • Thread
    • brain imaging fibrinogen long covid mri neuroinflammation perivascular spaces pet scan pf4 tspo vanelzakker
    • Replies: 22
    • Forum: Long Covid research
  3. SNT Gatchaman

    Platelet factors attenuate inflammation and rescue cognition in ageing, 2023, Schroer et al.

    Platelet factors attenuate inflammation and rescue cognition in ageing Schroer, Adam B.; Ventura, Patrick B.; Sucharov, Juliana; Misra, Rhea; Chui, M. K. Kirsten; Bieri, Gregor; Horowitz, Alana M.; Smith, Lucas K.; Encabo, Katriel; Tenggara, Imelda; Couthouis, Julien; Gross, Joshua D.; Chan...
  4. Mij

    NETosis induction reflects COVID-19 severity and long COVID: insights from a 2-center patient cohort study in Israel, 2023, Nitzan Krinsky et al

    Essentials Neutrophil extracellular trap formation (NETosis) induction levels by COVID-19 plasma correlate with illness severity, duration, platelet activation and coagulation factors. Long COVID syndrome is identified by elevated NETosis induction measurement in convalescent plasma of patients...
    • Mij
    • Thread
    • neutrophil elastase neutrophil extracellular traps pf4
    • Replies: 2
    • Forum: Long Covid research
  5. LarsSG

    Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC)..., 2022, Kell & Pretorius et al

    Abstract Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a major global health and economic burden. Previously, we provided evidence that there is a significant insoluble fibrin amyloid microclot load in the circulation of individuals with long COVID...
    • LarsSG
    • Thread
    • fibrin kallikreins kell long covid microclots pf4 platelets pretorius
    • Replies: 1
    • Forum: Long Covid research
  6. Andy

    Sustained VWF-ADAMTS13 axis imbalance and endotheliopathy in Long COVID syndrome is related to immune dysfunction, 2022, Fogarty et al

    Abstract Background Prolonged recovery is common after SARs-CoV-2 infection, however the pathophysiological mechanisms underpinning Long COVID syndrome remain unknown. VWF-ADAMTS13 imbalance, dysregulated angiogenesis and immuno-thrombosis are hallmarks of acute COVID-19. We hypothesized that...
    • Andy
    • Thread
    • adamts13 endothelial immune dysfunction pf4 platelets vwf
    • Replies: 2
    • Forum: Long Covid research
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