placebo

Active Albuterol or Placebo, Sham Acupuncture, or No Intervention in Asthma Michael E. Wechsler, John M. Kelley, Ingrid O.E. Boyd, Stefanie Dutile, Gautham Marigowda, Irving Kirsch, Elliot Israel, Ted J. Kaptchuk Published July 14, 2011 [Line breaks added] Background In prospective...

Abstract Objectives Placebo effects can relieve acute and chronic pain in both research and clinical treatments by learning mechanisms. However, the application of placebo-based treatment strategies in routine medical care is questioned. The current study investigated the opinions of patients...

Looking at the evidence for one of the things that tends to get quoted as a proven fact in discussions of placebo effect: "The BMJ tries to walk a middle ground. The review acknowledges that the evidence is inconsistent while still suggesting that colour might influence the effectiveness of a...

Neural circuit basis of placebo pain relief Chen, Chong; Niehaus, Jesse K.; Dinc, Fatih; Huang, Karen L.; Barnette, Alexander L.; Tassou, Adrien; Shuster, S. Andrew; Wang, Lihua; Lemire, Andrew; Menon, Vilas; Ritola, Kimberly; Hantman, Adam; Zeng, Hongkui; Schnitzer, Mark J.; Scherrer, Grégory...

Full article available: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482600

This much cited (over 1600 citations) study from 1978 claims to have proven the placebo effect is real. https://pubmed.ncbi.nlm.nih.gov/80579/

Journal of Clinical Epidemiology Homeopathy can offer empirical insights on treatment effects in a null field Matthew K Sigurdson, Kristin L Sainani, John P A Ioannidis Abstract Objectives: A "null field" is a scientific field where there is nothing to discover and where observed...

From a memoir piece in Guernica written by a doctor who treats chronic pain. He uses the hardware/software analogy. Feels like what's missing here is a discussion about regression to the mean?

how do i rationalise withdrawal of liothyronine (T3) in a symptomatic tired, depressed and vulnerable patient with chronic fatigue syndrome or long COVID who may or may not have hypothyroidism? https://www.endocrine-abstracts.org/ea/0086/ea0086hdi2.2 Endocrine Abstracts (2022) 86 HDI2.2 | DOI...

https://en.wikipedia.org/wiki/Placebo Just read the article which claims reference 4 proves this however after reading reference 4 (https://web.archive.org/web/20200522232756/https://www.cancer.org/treatment/treatments-and-side-effects/clinical-trials/placebo-effect.html) I couldn't find any...

Quackery is on the rise, and the placebo effect is part of the problem https://edzardernst.com/2022/06/quackery-is-on-the-rise-and-the-placebo-effect-is-part-of-the-problem/ Prof. Fabricio Benedetti is one of the world’s leading experts in the study of placebo effects. I have mentioned his...

Frequency of Adverse Events in the Placebo Arms of COVID-19 Vaccine Trials. A Systematic Review and Meta-analysis Julia W. Haas, PhD1,2; Friederike L. Bender, MS3; Sarah Ballou, PhD1,2; John M. Kelley, PhD1,4; Marcel Wilhelm, PhD3; Franklin G. Miller, PhD5; Winfried Rief, PhD3; Ted J...

An article about the paper Doctors Often Prescribe Placebos. But How Well Do They Work? An Australian researcher argues that the medical community has enshrined placebos as “mysterious and highly effective” in clinical care on the basis of flawed research. By Oscar Schwartz The New York Times...

Objective To determine whether trial-design, patient-type, or placebo-type factors influence the size of the placebo analgesic effect in clinical trials. Study Design and Setting Trials that measured pain outcomes in Hróbjartsson and Gøtzsche's meta-analysis were retrieved and coded for eight...

We have previously discussed interventions that manipulate how patients report symptoms as a separate form of bias, rather than as part of the placebo effect. Critics of the placebo effect have pointed out that according to the available evidence, "placebo effects are weak: regression to the...

A Systematic Review and Meta-analysis Key Points Question What is the placebo effect magnitude in different treatment modalities used for management of patients with treatment-resistant depression? Findings In this systematic review and meta-analysis of 3228 patients with...

Abstract This commentary provides the authors’ point of view about the biopsychosocial perspective of placebo effect on musculoskeletal pain in the rehabilitation field. Key Summary Points Rehabilitation interventions, including physical therapies, play a leading role in the management of...

Full reference: Boot, W. R., Simons, D. J., Stothart, C., & Stutts, C. (2013). The pervasive problem with placebos in psychology: Why active control groups are not sufficient to rule out placebo effects. Perspectives on Psychological Science, 8(4), 445-454. Link to fulltext...

Just came across this and thought it might be of interest (its not new, its from 2004) Moncrieff, J., Wessely, S., & Hardy, R. (2004). Active placebos versus antidepressants for depression. Cochrane database of systematic reviews, CD003012.PUB2...

Darragh, M., Chang, J. W.-H., Booth, R. J., & Consedine, N. S. (2015). The placebo effect in inflammatory skin reactions. Journal of Psychosomatic Research, 78(5), 489–494. doi:10.1016/j.jpsychores.2015.01.011 ResearchGate link here Scihub link here This study found that a placebo cream...