prostaglandins

  1. jnmaciuch

    COX-1 inhibitors (NSAIDs/acetaminophen) before activity to prevent/lessen PEM

    Hi all, I saw some discussion of NSAIDs already here: https://www.s4me.info/threads/nsaids.6504/ I wanted to make another thread specifically to talk about the timing of when NSAIDs are taken, and if that has an effect on helping with symptoms. Added: I'm only discussing NSAIDs for my...
  2. Andy

    Increased galanin-galanin receptor 1 signaling, inflammation, and insulin resistance are associated with affective symptoms and CFS... Maes et al

    Full title: Increased galanin-galanin receptor 1 signaling, inflammation, and insulin resistance are associated with affective symptoms and chronic fatigue syndrome due to long COVID Abstract Background Patients with Long COVID (LC) often experience neuropsychiatric symptoms such as...
  3. SNT Gatchaman

    PGE2 and HCN2 ion channels are critical mediators of pain initiated by angiotensin II, 2024, Pinto et al.

    PGE2 and HCN2 ion channels are critical mediators of pain initiated by angiotensin II Pinto; Vilar; McNaughton Angiotensin II is well known to have an important influence on blood pressure, mediated via the angiotensin II type 1 receptor (AT1R), and more recent studies have shown that...
  4. Nightsong

    Preprint Increased CRTH2 Expression in Postural Orthostatic Tachycardia Syndrome, 2024, Abdallah+

    Purpose: The exact etiology of Postural Orthostatic Tachycardia Syndrome (POTS) is still unknown but is likely heterogeneous and multifaceted, involving autoimmune, neuropathic, hypovolemic, and hyperadrenergic pathways. Recently, more research has been devoted to understanding POTS’s underlying...
  5. Mij

    Mild to moderate post-Covid19 alters markers of lymphocyte activation, exhaustion . . . assoc by physical activity-level, 2023, Spolador de Alencar

    Full title: Mild to moderate post-Covid-19 alters markers of lymphocyte activation, exhaustion, and immunometabolic responses that can be partially associated by physical activity-level- and observational sub-analysis fit- Covid study, 2023, Bruna Spolador de Alencar Silva et al Aim: This study...
  6. Andy

    Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID 2023 Scott et al

    Abstract Background COVID-19 is associated with a dysregulated immune response but it is unclear how immune dysfunction contributes to the chronic morbidity persisting in many COVID-19 patients during convalescence (long COVID). Methods We assessed phenotypical and functional changes of...
  7. Andy

    An airway-to-brain sensory pathway mediates influenza-induced sickness 2023 Bin et al

    Abstract Pathogen infection causes a stereotyped state of sickness that involves neuronally orchestrated behavioural and physiological changes1,2. On infection, immune cells release a ‘storm’ of cytokines and other mediators, many of which are detected by neurons3,4; yet, the responding neural...
  8. SNT Gatchaman

    Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes, 2021, Richardson et al

    Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes Edward Richardson, David García-Bernal, Eleonora Calabretta, Rubén Jara, Marta Palomo, Rebecca M Baron, Gregory Yanik, Jawed Fareed, Israel Vlodavsky, Massimo Iacobelli, Maribel...
  9. H

    Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis (2018) De Meirleir et al

    https://www.ncbi.nlm.nih.gov/pubmed/30463572 https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1696-z
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