randomized controlled trial

Some details are now know. I'm not happy about Chalder fatigue scale being used as primary outcome. https://clinicaltrials.gov/ct2/show/NCT03691987

For those interested: On Thursday 26 October, 11.00-12.00 PDT, Dr Regina Nuzzo and Dr Kristin Sainani will give a free webinar on what a good clinical trial should look like. I expect it to have a relatively low treshold, followable for beginners as well. I got the invitation as a student of...

The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial Leitman, Marina; Fuchs, Shmuel; Tyomkin, Vladimir; Hadanny, Amir; Zilberman-Itskovich, Shani; Efrati, Shai Post-COVID-19 condition refers to a range of persisting...

Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial Carolyn T Bramante; Kenneth B Beckman; Tanvi Mehta; Amy B Krager; David J Odde; Christopher J Tignanelli; John B Buse; Darnell M Johnson; Ray H B Watson; Jerry J Daniel; David M Liebovitz; Jacinda M Nicklas...

Access to individual patient-level data (IPD) of randomized clinical trials (RCTs) increases the reproducibility of research, facilitates exploration of effect modifiers, and leverages research investments beyond the original research question. This study aimed to describe access to IPD of RCTs...

Several posts have been moved from this thread: Ampligen - Hemispherx Biopharma re ME/CFS not relating to ME but Covid-19 AIM ImmunoTech inks deal to research vaping device as a vehicle for Ampligen to treat coronavirus...

Background Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a severely debilitating disease of unknown pathogenesis consisting of a variety of symptoms including severe fatigue. The objective of the study was to examine the efficacy and safety of a TLR-3 agonist, rintatolimod...

Wessely was the senior author of the article & Chalder was a trial investigator. Background: Fatigue is a common symptom for which patients consult their doctors in primary care. With usual medical management the majority of patients report that their symptoms persist and become chronic. There...

"Ian Harris explains that more than half of commonly performed surgical operations may be placebos. Adequate studies using a blinded control group are essential." "Ian Harris, a Professor of Orthopaedic Surgery at the University of New South Wales in Sydney, Australia, wrote a book titled...