Redefining the role of Hypoxia-inducible factors HIFs in oxygen homeostasis
Clemente Fernández Arias; Franciso J Acosta; Federica Bertocchini; Cristina Fernández-Arias
Hypoxia-inducible factors (HIFs) are key regulators of intracellular oxygen homeostasis. The marked increase in HIFs activity...
Abstract
Sustained smouldering, or low-grade activation, of myeloid cells is a common hallmark of several chronic neurological diseases, including multiple sclerosis1. Distinct metabolic and mitochondrial features guide the activation and the diverse functional states of myeloid cells2...
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