Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study
Eleni Friligkou, Solveig Løkhammer, Brenda Cabrera-Mendoza, Jie Shen, Jun He, Giovanni Deiana, Mihaela Diana Zanoaga, Zeynep Asgel, Abigail Pilcher, Luciana Di Lascio...
Albuminuria and Mental Illness Risk: Results From National Health and Nutrition Examination Survey 2005–2018 and Mendelian Randomization Analyses
Yangyang Wang, Sen Li
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Background
Recent evidence suggests a link between albuminuria and mental illness. However, whether this...
The hypothesis of biologically based subtypes of schizophrenia: a 10-year update
Oliver D. Howes, Bernard R. Bukala, Sameer Jauhar, Robert A. McCutcheon
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A decade ago we proposed that there are two biological subtypes of schizophrenia: type A...
Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions
Christina Dardani, Jamie W. Robinson, Hannah J. Jones, Dheeraj Rai, Evie Stergiakouli, Jakob Grove, Renee Gardner, Andrew M. McIntosh, Alexandra Havdahl, Gibran...
Toxoplasma gondii as a Causal Factor in Schizophrenia: Evidence from Two Large Cohorts
Ariel Israel, Avi Weizman, Sarah Israel, Joshua Stokar, Shai Ashkenazi, Shlomo Vinker, Eli Magen, Eugene Merzon
Background
Schizophrenia (SCZ) is a debilitating psychiatric disorder with a complex and poorly...
Molecular overlaps of neurological manifestations of COVID-19 and schizophrenia from a proteomic perspective
Antunes, André S. L. M.; Reis-de-Oliveira, Guilherme; Martins-de-Souza, Daniel
COVID-19, a complex multisystem disorder affecting the central nervous system, can also have psychiatric...
SARS-CoV-2 Infection is Associated with an Increase in New Diagnoses of Schizophrenia Spectrum and Psychotic Disorder: A Study Using the US National COVID Cohort Collaborative N3C
Asif Rahman; Michael Russell; Wanhong Zheng; Daniel Eckrich; Imtiaz Ahmed; on behalf of the N3C Consortium
Amid the...
Prioritization of potential causative genes for schizophrenia in placenta
https://www.nature.com/articles/s41467-023-38140-1
Abstract
Our earlier work has shown that genomic risk for schizophrenia converges with early life complications in affecting risk for the disorder and sex-biased...
Sex differences in the blood-brain barrier: Implications for mental health
Dion-Albert L, Bandeira Binder L, Daigle B, Hong-Minh A, Lebel M, Menard C
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia (SZ) are increasing at...
Comer Ashley L., Carrier Micaël, Tremblay Marie-Ève, Cruz-Martín Alberto (2020),
The Inflamed Brain in Schizophrenia: The Convergence of Genetic and Environmental Risk Factors That Lead to Uncontrolled Neuroinflammation, Frontiers in Cellular Neuroscience 14 (2020), DOI...
In a new blog series, we will investigate how illnesses were once thought to result from stress, psychological disturbance, or deviant personality features. From the cancer-prone personality to the theory of ‘refrigerator mothers’, medicine appears to suffer from a recurrent tendency to...
autism
bruno bettelheim
critical
dunbar
eysenck
franz alexander
grossarth-maticek
long covid
me/cfs skeptic
psychosomatic
psychosomatic medicine
refrigerator mother
rheumatoid arthritis
schizophrenia
susan sontag
Abstract
The importance of tryptophan as a precursor for neuroactive compounds has long been acknowledged. The metabolism of tryptophan along the kynurenine pathway and its involvement in mental disorders is an emerging area in psychiatry.
We performed a meta-analysis to examine the...
Full title: Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways
I'd suggest that there is total conflation between chronic fatigue and 'chronic fatigue syndrome' here.
Paywall...
Pre-print:
https://www.preprints.org/manuscript/202003.0432/v1
Chronic Fatigue Syndrome and Fibromyalgia-Like Symptoms Are an Integral Component of the Phenome of Schizophrenia: Neuro-Immune and Opioid System Correlates
Alpha7 Nicotinic Receptors as Therapeutic Targets in Schizophrenia Jason R Tregellas, PhD, Korey P Wylie, MD
https://academic.oup.com/ntr/article/21/3/349/5078145
The role of a recently discovered Alpha-7 nicotinic acetylcholine receptor on amyloid-beta pathology in Alzheimer's disease...
The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice (2019), Peng Zheng et al
http://advances.sciencemag.org/content/5/2/eaau8317
Abstract:
Do we know if anyone has tried transferring faecal samples from...
An interesting correlation between use of these medications and reduced symptoms in a large scale study.
One proposed mechanism is a reduction in inflammation.
Neuroscience News :
https://neurosciencenews.com/statins-mental-health-10473/
SMC reaction ...
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