spaceflight

In summary, the findings demonstrated that increasing difficulty levels in the cognitive task resulted in reduced accuracy, prolonged response times, and increased perceived difficulty scores. Task performance remained unaffected by the inclination levels. Additionally, the results revealed an...

Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space Moreno-Villanueva, Maria; Jimenez-Chavez, Luis E.; Krieger, Stephanie; Ding, Liang-Hao; Zhang, Ye; Babiak-Vazquez, Adriana; Berres, Mark; Splinter...

Neurophysiological and Cognitive Changes Induced by the Acute Head-Down Tilt Monika Sharma; Savita Gaur; Harsh Pawar; Neha Yadav: Bhanuteja Thondala; Sanjeev Kumar; Krishna Kishore; Koushik Ray; Usha Panjwani INTRODUCTION In space, under weightlessness conditions, human brain activity is...

Researchers sent engineered heart tissue to the International Space Station and measured how it faired. The study offers a useful means of identifying the molecular pathways behind the detrimental effects of spaceflight on the human heart, says Joseph Wu, a cardiologist at Stanford University...

Spaceflight alters host-gut microbiota interactions Gonzalez, E.; Lee, M. D.; Tierney, B. T.; Lipieta, N.; Flores, P.; Mishra, M.; Beckett, L.; Finkelstein, A.; Mo, A.; Walton, P.; Karouia, F.; Barker, R.; Jansen, R. J.; Green, S. J.; Weging, S.; Kelliher, J.; Singh, N. K.; Bezdan, D.; Galazska...

Effects of spaceflight on the brain Rachael D Seidler; Xiao Wen Mao; Grant D Tays; Tianyi Wang; Peter zu Eulenburg SUMMARY The number of long duration human spaceflights has increased substantially over the past 15 years, leading to the discovery of numerous effects on the CNS. Microgravity...

Abstract Spending time in a microgravity environment is known to cause significant skeletal muscle atrophy and weakness via muscle unloading, which can be partly attributed to Ca2+ dysregulation. The sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) pump is responsible for bringing Ca2+ from...

In-depth studies include first health data collected from space tourists NASA and other space agencies have studied the health of hundreds of astronauts over the past 6 decades, finding a wide range of impacts, including elevated long-term cancer risks from exposure to space radiation, muscle...

Disuse-Induced Muscle Fatigue: Facts and Assumptions Sergeeva, Xenia V.; Lvova, Irina D.; Sharlo, Kristina A. Skeletal muscle unloading occurs during a wide range of conditions, from space flight to bed rest. The unloaded muscle undergoes negative functional changes, which include increased...

Gut permeability among Astronauts during Space missions Akinsuyi; Xhumari; Ojeda; Roesch The space environment poses substantial challenges to human physiology, including potential disruptions in gastrointestinal health. Gut permeability has only recently become widely acknowledged for its...

Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight Anurag Sakharkar; Kiven Erique Lukong; Lauren M Sanders; Sylvain V Costes; Jian Yang; Changiz Taghibiglou Space exploration has captured the imagination of humanity for generations. From the first steps on the moon to...

I haven't had the chance to watch this yet, but the speakers are the two senior authors of Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts (2023)

Artificial gravity during a spaceflight analog alters brain sensory connectivity McGregor; Lee; Mulder; De Dios; Beltran; Wood; Bloomberg; Mulavara; Seidler Spaceflight has numerous untoward effects on human physiology. Various countermeasures are under investigation including artificial...

DNA methylation dynamics associated with long-term isolation of simulated space travel Fei Hou; Xu Zhou; Shunheng Zhou; Haizhou Liu; Yu-e Huang; Mengqin Yuan; Jicun Zhu; Xinyu Cao; Wei Jiang Long-term isolation is one of the risk factors that astronauts will encounter in spaceflight. At present...

Latent virus reactivation in astronauts on the international space station Mehta, Satish K.; Laudenslager, Mark L.; Stowe, Raymond P.; Crucian, Brian E.; Feiveson, Alan H.; Sams, Clarence F.; Pierson, Duane L. Reactivation of latent herpes viruses was measured in 23 astronauts (18 male and 5...

Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact Willian A. da Silveira; Hossein Fazelinia; Sara Brin Rosenthal; Evagelia C. Laiakis; Man S. Kim; Cem Meydan; Yared Kidane; Komal S. Rathi; Scott M. Smith; Benjamin Stear; Yue Ying...

Decreases in maximal oxygen uptake following long-duration spaceflight: Role of convective and diffusive O2 transport mechanisms C. J. Ade, R. M. Broxterman, A. D. Moore, and T. J. Barstow Abstract We have previously predicted that the decrease in maximal oxygen uptake (V̇o2max) that...

Vascular and Microvascular Dysfunction Induced by Microgravity and Its Analogs in Humans: Mechanisms and Countermeasures Nastassia Navasiolava, Ming Yuan, Ronan Murphy, Adrien Robin, Mickael Coupé, Linjie Wang, Asmaa Alameddine, Guillemette Gauquelin-Koch, Claude Gharib, Yinghui Li and...

Cardiovascular deconditioning during long-term spaceflight through multiscale modeling Gallo, C., Ridolfi, L. & Scarsoglio, S. Abstract Human spaceflight has been fascinating man for centuries, representing the intangible need to explore the unknown, challenge new frontiers, advance technology...

Based on results in mice, but may be of interest. Paywall, https://www.sciencedirect.com/science/article/pii/S0271531718311230?via%3Dihub Sci Hub, https://sci-hub.se/10.1016/j.nutres.2018.12.013