t cell receptor

  1. SNT Gatchaman

    HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity, 2025, Zhang et al.

    HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity Type 1 narcolepsy (T1N), an autoimmune disease associated with a disruption of hypocretin/orexin neurons, has conserved genetic effects transcending cultures and ethnicities. We pooled data...
  2. SNT Gatchaman

    HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes, 2025, Rowntree et al.

    HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes Understanding host factors driving asymptomatic versus severe disease outcomes is of key importance if we are to control emerging and re-emerging viral infections. HLA-B*15:01 has been...
  3. Hutan

    Genetics: BTN2A2 and BTN3A3

    DecodeME candidate ME/CFS gene CHROMOSOME 6p Chr6p contained seven Tier 1 genes. *************************** BTN2A2 (Tier 1) • Protein: Butyrophilin subfamily 2 member A2. UniProt. GeneCards. The allele that increases the risk of ME/CFS is associated with decreasing BTN2A2 gene expression...
  4. SNT Gatchaman

    SARS-CoV-2-specific CD8+ T cells from people with [LC] establish and maintain effector phenotype and key TCR signatures over 2 years, 2024, Rowntree+

    SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years Rowntree, Louise C.; Audsley, Jennifer; Allen, Lilith F.; McQuilten, Hayley A.; Hagen, Ruth R.; Chaurasia, Priyanka; Petersen, Jan; Littler, Dene R.; Tan...
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