Exploring Hypercoagulability in Post-COVID Syndrome PCS: An Attempt at Unraveling the Endothelial Dysfunction
Muys, Maxim; Demulder, Anne; Besse-Hammer, Tatiana; Ghorra, Nathalie; Rozen, Laurence
BACKGROUND
The lingering effects of SARS-CoV-2 infection, collectively known as post-COVID syndrome...
Abstract:
The hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity. In coronavirus disease 2019 (COVID-19), dysregulation of the hemostatic and complement systems has been...
Proinflammatory Mediators, IL Interleukin-1β, TNF Tumor Necrosis Factor α, and Thrombin Directly Induce Capillary Tube Regression
Gretchen M. Koller; Christopher Schafer; Scott S. Kemp; Kalia N. Aguera; Prisca K. Lin; Joshua C. Forgy; Courtney T. Griffin; George E. Davis
OBJECTIVE: In this...
Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19?
Gerencer, Marijan; McGuffin, Liam J.
The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that...
Abstract
Background
Persistent symptoms including breathlessness, fatigue and decreased exercise tolerance have been reported in patients after acute SARS-CoV-2 infection. The biological mechanisms underlying this ‘Long COVID’ syndrome remain unknown. However, autopsy studies have highlighted...
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