Rather than do a separate thread for each paper, I figured I would make one thread pulling together a couple findings and see if there's any potential relevance to ME/CFS.
CRH is of interest from the ME/CFS autopsy study preliminary results, discussed here...
Sars-Cov-2 spike protein and plasma from COVID-19 patients induce extracellular traps by myeloid-derived suppressor cells
INTRODUCTION
Polymorphonuclear-myeloid-derived suppressor cells (PMN-MDSC) are elevated in COVID-19 patients, playing a crucial role in suppressing the SARS-CoV-2 specific...
https://www.medrxiv.org/content/10.1101/2025.02.04.25320937v1.full.pdf+html
New Precision Life preprint that was shared by Chris Ponting in Bluesky today. Looks very interesting.
The Complex World of Kynurenic Acid: Reflections on Biological Issues and Therapeutic Strategy
Stone, Trevor W.; Darlington, L. Gail; Badawy, Abdulla A.-B.; Williams, Richard O.
It has been unequivocally established that kynurenic acid has a number of actions in a variety of cells and tissues...
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