tregs

  1. Nightsong

    Meningeal regulatory T cells inhibit nociception in female mice, 2025, Midavaine+

    Abstract: T cells have emerged as orchestrators of pain amplification, but the mechanism by which T cells control pain processing is unresolved. We found that regulatory T cells (Treg cells) could inhibit nociception through a mechanism that was not dependent on their ability to regulate immune...
  2. E

    Regulatory T cells shield muscle mitochondria from interferon-γ–mediated damage to promote the beneficial effects of exercise, 2023, Mathis et al

    Regulatory T cells shield muscle mitochondria from interferon-γ–mediated damage to promote the beneficial effects of exercise Editor’s summary Regulatory T cells (Tregs) support repair of injured muscle, but whether they participate in the response of healthy muscle to exercise training remains...
  3. Andy

    The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries 2023 Hanna et al

    Highlights Muscle injury induces local accumulation of RORγ+ Treg cells emanating from the gut The microbiota regulates muscle repair via RORγ+ Treg cells Muscle RORγ+ Treg cells shield differentiating muscle stem cells from IL-17A RORγ+ Treg cell emissaries play a general role in the...
  4. Andy

    A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients – indications for their potential involvement in... LC 2022 Haunhorst

    Full title: A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients – indications for their potential involvement in the development of Long COVID? Background: Recovery from coronavirus disease 2019 (COVID-19) can be impaired by the persistence of symptoms or new-onset...
  5. Mij

    Mining the microbiota to identify gut commensals modulating neuroinflammation in a mouse model of multiple sclerosis, 2022, Paola Bianchimano et al

    Abstract Background The gut microbiome plays an important role in autoimmunity including multiple sclerosis and its mouse model called experimental autoimmune encephalomyelitis (EAE). Prior studies have demonstrated that the multiple sclerosis gut microbiota can contribute to disease, hence...
  6. Andy

    Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism, 2021, Li et al

    Abstract. Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that Esrrg controls regulatory T cells (Treg) through mitochondria homeostasis. Esrrg deficiency impaired the maintenance and function of Treg cells...
  7. Colin

    Follicular regulatory T cells produce neuritin to regulate B cells (2021) Gonzalez-Figueroa et al

    Summary Regulatory T cells prevent the emergence of autoantibodies and excessive IgE, but the precise mechanisms are unclear. Here, we show that BCL6-expressing Tregs, known as follicular regulatory T (Tfr) cells, produce abundant neuritin protein that targets B cells. Mice lacking Tfr cells or...
  8. John Mac

    Impact of Long-Term Cryopreservation on Blood Immune Cell Markers in ME/CFS: Implications for Biomarker Discovery Gomez-Mora et al 2020

    Full title: Impact of Long-Term Cryopreservation on Blood Immune Cell Markers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for Biomarker Discovery https://www.frontiersin.org/articles/10.3389/fimmu.2020.582330/full
  9. Andy

    Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis, 2019, Song et al

    In mice. Paywall, https://www.nature.com/articles/s41586-019-1865-0 Sci hub, https://sci-hub.se/10.1038/s41586-019-1865-0 ETA: Added "In mice".
  10. Andy

    Bile acid metabolites control TH17 and Treg cell differentiation, 2019, Hang et al

    In mice. Paywall, https://www.nature.com/articles/s41586-019-1785-z Sci hub, https://sci-hub.se/10.1038/s41586-019-1785-z
  11. Andy

    microRNA-142–mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance, 2019, Lord et al

    Open access at https://www.jci.org/articles/view/124725 Press release about the paper https://www.manchester.ac.uk/discover/news/masterswitch-discovered-in-bodys-immune-system/
  12. Indigophoton

    Immune cells can switch from ‘gang members’ to ‘police officers’

    https://www.imperial.ac.uk/news/187131/immune-cells-switch-from-gang-members/
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