Longitudinal positron emission tomography and postmortem analysis reveals widespread neuroinflammation in SARS-CoV-2 infected rhesus macaques
Nieuwland, Juliana M.; Nutma, Erik; Philippens, Ingrid H. C. H. M.; Böszörményi, Kinga P.; Remarque, Edmond J.; Bakker, Jaco; Meijer, Lisette; Woerdman...
Abstract
The brain is an energy hog, consuming available energy supplies at a rate out of all proportion to its relatively small size. This outsized demand, largely reflecting the unique computational activity of the brain, is met by an ensemble of neurovascular coupling mechanisms that link...
In mice.
https://www.biorxiv.org/content/10.1101/2021.08.02.454769v1
TL;DR: microglia can influence cerebral vasculature.
(Paragraphs mine for legibility)
Microglia are brain-resident immune cells with a repertoire of functions in the developing, mature and pathological brain. Their...
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