viral infections

STING recognition of viral dsDNA by nociceptors mediates pain in mice https://www.sciencedirect.com/science/article/pii/S0889159124004823 Highlights Nociceptors can directly sense viral nucleic acids, such as dsDNA derived from herpes and vaccinia viruses. Cytosolic dsDNA causes nocifensive...

Global organelle profiling reveals subcellular localization and remodeling at proteome scale Marco Y Hein; Duo Peng; Verina Todorova; Frank McCarthy; Kibeom Kim; Chad Liu; Laura Savy; Camille Januel; Rodrigo Baltazar-Nunez; Sophie Bax; Shivanshi Vaid; Madhuri Vangipuram; Ivan E Ivanov; Janie R...

Host Calcium Channels and Pumps in Viral Infections Xingjuan Chen,1,2 Ruiyuan Cao,2,* and Wu Zhong2,* Ca2+ is essential for virus entry, viral gene replication, virion maturation, and release. The alteration of host cells Ca2+ homeostasis is one of the strategies that viruses use to modulate...

COVID-19 Neuropathology: evidence for SARS-CoV-2 invasion of Human Brainstem Nuclei Aron Emmi, Stefania Rizzo, Luisa Barzon, Michele Sandre, Elisa Carturan, Alessandro Sinigaglia, Silvia Riccetti, Mila della Barbera, Rafael Boscolo-Berto, Patrizia Cocco, Veronica Macchi, Angelo Antonini, Monica...

My ME/CFS was apparently triggered by a virus. In late Dec. 1989 I got sick on a plane. We were returning from a trip to India (family visit). I was sick for more than a week - maybe 9-10 days? But there were no tests done to see what the virus was. I don't know if that's because of where I...

Abstract Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and may represent a factor that...

Zika virus (ZIKV) is an arbovirus belonging to Flaviviridae family that emerged as a global health threat due to its association with microcephaly and other severe neurological complications, including Guillain-Barré Syndrome (GBS) and Congenital Zika Syndrome (CZS). ZIKV disease has been linked...

An interesting article on a possible association between Long Covid and EBV reactivation, thank you Anil (sorry forgotten your user name here) for alerting me to this on Facebook: Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation Gold et al Pathogens...

The possibility of ME/CFS being caused by a chronic viral (or other) infection – for at least some people — has been discussed for a long time. The biggest piece of evidence in favour of t is that infections are very often a trigger for ME/CFS (summary of the evidence here). A similar case has...

Though the title says chronic fatigue the article is about chronic fatigue syndrome https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02666-5

Not a new study, it's from 2011, but thought it might be of use posted on the forum. Open access, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633594/

For as long as I have been reading viral research, which is coming up on a decade, there have been some pretty vicious academic fights over the criteria necessary to establish a disease as a viral infection. In the very obscure field of multipart viruses in plants there has recently been an...

I have yet to read the paper but at first glance this sounds like a really neat piece of research - an interesting serendipitous discovery, thoroughly followed up. https://phys.org/news/2018-03-infection-dodging-stem-cells-tactics-viral.amp Full paper: Xianfang Wu et al. Intrinsic Immunity...

This thread has been split from here. CDC-funded study: BMJ. 2006 Sep 16;333(7568):575. Epub 2006 Sep 1. Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study. Hickie I1, Davenport T, Wakefield D, Vollmer-Conna U, Cameron B, Vernon...