Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Abu Mohammad Syed; Alexander K. Karius; Jin Ma; Ping-yuan Wang; Paul M. Hwang
ME/CFS is a debilitating multisystem disorder of unclear etiology that affects many individuals worldwide. One of its hallmark symptoms...
Preprint posted on MedRxiv, now posted with new title on SSRN, see post #4
Integrative Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization Reveal Risk Loci for Long COVID
Zhongshan Cheng
Abstract
Long COVID presents a significant public health challenge...
Link: Assessment of the therapeutic potential of salubrinal for ME/CFS and long-COVID - ScienceDirect
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic debilitating condition with no cure that shares commonality with long-COVID. This review examines current...
Abstract:
We start by constructing gene-gene association networks based on about 300 genes whose expression values vary between the groups of CFS patients (plus control). Connected components (modules) from these networks are further inspected for their predictive ability for symptom severity...
bip
endoplasmic reticulum
er stress
exercise intolerance
grp78
mitochondrial function
mouse model
muscle biopsy
p53
perk
salubrinal
seahorse
study idea
wasf3
wave3
https://www.mdpi.com/2218-273X/11/2/173/htm
Abstract
Recent studies undoubtedly show the importance of inter organellar connections to maintain cellular homeostasis. In normal physiological conditions or in the presence of cellular and environmental stress, each organelle responds alone or in...
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