Highlights
• Dengue and Zika viruses alter endoplasmic reticulum-mitochondria contact sites (ERMC)
• Mitochondrial respiration is perturbed over the course of the infection
• ERMC protein knockdown increases viral replication
• ERMC proteins RRBP1 and SYNJ2BP regulate Zika virus-induced cell...
Zika virus (ZIKV) is an arbovirus belonging to Flaviviridae family that emerged as a global health threat due to its association with microcephaly and other severe neurological complications, including Guillain-Barré Syndrome (GBS) and Congenital Zika Syndrome (CZS). ZIKV disease has been linked...
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