Clinically relevant proteins can be difficult to distinguish against a background of more abundant molecules. The SomaScan® Assay offers a way to decipher proteomic health signatures. The pathology of most diseases can be traced back to the influence of a handful of proteins, and the ability to identify the relevant molecules in blood or other biological samples can guide the development of more accurate diagnostics and effective drugs. But that signal can be drowned out by vast noise levels. The concentrations of individual proteins can vary by more than 10 orders of magnitude in the blood, meaning that one molecule might be billions of times scarcer than another in the same sample. https://www.nature.com/articles/d42473-022-00342-4
