[This seems to be only very tenuously about ME/CFS] Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology and without effective treatment options. The onset of ME/CFS is often associated with neuroinflammation following bacterial or viral infection. A positron emission tomography imaging study revealed that the degree of neuroinflammation was correlated with the severity of several symptoms in patients with ME/CFS. In animal studies, lipopolysaccharide- and polyinosinic-polycytidylic acid-induced models are thought to mimic the pathological features of ME/CFS and provoke neuroinflammation, characterized by increased levels of proinflammatory cytokines and activation of microglia. In this review, we described the anti-inflammatory effects of three compounds on neuroinflammatory responses utilizing animal models. The findings of the included studies suggest that anti-inflammatory substances may be used as effective therapies to ameliorate disease symptoms in patients with ME/CFS. Open access, https://www.frontiersin.org/articles/10.3389/fneur.2022.890217/full
There are no new studies here, it's a review of previous work, mostly by these authors. We'd have to look at the references to see how strong the results are. The conclusion suggests the authors are looking to trial these treatments in people with ME/CFS.
"Finally, 6-MSITC derived from Wasabi" Not sure how keen I would be on trying a patented "wasabi up the bum" treatment, to be honest...
