Article: Gut-brain axis and psychobiotics

Andy

Retired committee member
"Psychobiotics" :rolleyes:
Increased amounts of “good bacteria” in our intestines are being associated with the ability to curb inflammation, reduce cortisol levels, lower stress, alleviate symptoms of anxiety and depression, improve memory, and even lessen social anxiety.

This demonstrates that beneficial intestinal bacteria (even in the form of probiotics) may function as vehicles to deliver neuroactive compounds, forming in turn the gut-brain interaction called the gut-brain axis. This has given rise to the term ‘psychobiotic’, which represents a live organism that, when taken in appropriate amounts, provides certain health benefits for patients with psychiatric illnesses.
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Altering the ratio of anti-inflammatory to pro-inflammatory cytokines has been proposed to be an effective mechanism of psychobiotics. Bacillus infantis and Lactobacillus casei were shown to possess the most beneficial effects, especially in patients with chronic fatigue syndrome.
https://www.news-medical.net/health/Gut-brain-axis-and-psychobiotics.aspx
 
Perhaps its that I don't know enough yet, but I always get the feeling that the gut/microbiome is the NEXT BIG THING. And I feel sceptical about the scope of the claims being made.

I had a look at some of the references in that article, and they seemed to be making strong claims on pretty tenuous evidence. The only really empirical one was this one. It reviews a variety of trials (RCTs), which appear to show that probiotics can improve whatever ails you psychologically - be it a mild case of stress or full on depression.

hmmmm
 
Perhaps its that I don't know enough yet, but I always get the feeling that the gut/microbiome is the NEXT BIG THING. And I feel sceptical about the scope of the claims being made.

Indeed and remember that poo has been the NEXT BIG THING for over a century now. It is the reasons why Germans have loos that allow you to carefully inspect your poo every day. Poo was the great big thing early in the twentieth century when everything was treated with fish diets and what not. Poo has always been big. It has just been re-branded as 'microbiome'.
 
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