Preprint Assessing the Relationship in Symptomology of Myalgic Encephalitis/Chronic Fatigue Syndrome and Long Covid, 2024, Hardigan

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4988677

Assessing the Relationship in Symptomology of Myalgic Encephalitis/Chronic Fatigue Syndrome and Long Covid

11 Pages Posted: 29 Oct 2024

Abstract

The symptomology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) has been found to have many commonalities with Long Covid (LC) symptomology.

The objective of this study was to more clearly define the comparison between ME/CFS and LC in terms of symptomology.

A cross-sectional analysis of 27,651 interviewees from an NHIS 2022 adult dataset was conducted. The data was controlled for subject’s sex, race/ethnicity, age, life satisfaction, insurance coverage, poverty ratio, and comorbidities.

A logistic regression was used to compare four groups: (1) LC individuals, (2) ME/CFS individuals, (3) LC with ME/CFS individuals, and (4) Controls by symptoms of depression, anxiety, physical activity, fatigue, and memory.

The results demonstrated that subjects with both ME/CFS and LC were more likely to report memory issues, anxiety, depression, fatigue, and difficulty with physical activity followed by subjects with ME/CFS only, LC only, and the controls (p<0.01).

Our study suggests a synergistic mechanism between ME/CFS and LC in developing issues with anxiety, depression, fatigue, and physically activity in patients.

The conclusions of this study propose a need to elucidate the possible overlap in pathophysiological mechanisms of ME/CFS and LC in the symptomology of patients.

Highlights:

 Long Covid alone is less likely to express symptomology than ME/CFS alone.

 ME/CFS and Long Covid are more likely to express symptomology than conditions alone.

 A greater number of women are reported to have these conditions.

 

Why use 'myalgic encephalitis' in the title and keywords, but 'myalgic encephalomyelitis' in the main text? Can only assume this is sloppiness.

 

Another error: "physically activity".

 

Now published:

https://www.sciencedirect.com/science/article/pii/S2667036424000220
American Journal of Medicine Open
Available online 1 February 2025, 100085
In Press, Journal Pre-proof
Clinical Research Study
Assessing the relationship in symptomology of Myalgic Encephalitis/Chronic Fatigue Syndrome and Long Covid

Nikitha Garapaty , Kristina M. Reyes , Lily Tehrani , Maximiliano Barbosa Mendoza , Patrick Hardigan

open access

Highlights

• •
  Long Covid alone is less likely to express symptomology than ME/CFS alone.
• •
  ME/CFS and Long Covid are more likely to express symptomology than conditions alone.
• •
  A greater number of women are reported to have these conditions.

Abstract

The symptomology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) shares many commonalities with Long Covid.

This study aimed to clearly define the comparison between ME/CFS and LC in terms of symptomology.

A cross-sectional analysis of 27,651 interviewees from an NHIS 2022 adult dataset was conducted.

The data was controlled for subject's sex, race/ethnicity, age, life satisfaction, insurance coverage, poverty ratio, and comorbidities.

A logistic regression was used to compare four groups: (1) LC individuals, (2) ME/CFS individuals, (3) LC with ME/CFS individuals, and (4) Controls by symptoms of depression, anxiety, physical activity, fatigue, and memory.

the results showed that subjects with both ME/CFS and LC were more likely to report memory issues, anxiety, depression, fatigue, and difficulty with physical activity followed by subjects with ME/CFS only, LC only, and the controls (p<0.01).

Our study suggests a synergistic mechanism between ME/CFS and LC in developing issues with anxiety, depression, fatigue, and physically activity in patients.

the study's conclusions highlight the need to elucidate the possible overlap in pathophysiological mechanisms of ME/CFS and LC in the symptomology of patients.

Keywords
Long COVID (LC)
Myalgic Encephalitis (ME)
Chronic Fatigue Syndrome (CFS)
Abbreviations
ME/CFS
Myalgic Encephalitis/Chronic Fatigue Syndrome
LC
Long Covid
NHIS
National Health Interview Survey