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https://healthcare-bulletin.co.uk/a...atigue-syndrome-a-cross-sectional-study-3312/
Research Article | Volume 15 Issue 5 (May, 2025) | Pages 120 - 124
Assessment of Vitamin D Deficiency Prevalence in Adults with Chronic Fatigue Syndrome: A Cross-Sectional Study
Pon. Saranya1
Vikrannth Vasanthakumar2
N. Deepthi3
1
Assistant Professor, Department of General Medicine, Govt Thiruvannamalai Medical College and Hospital, India
2
Associate Professor, Department of General Medicine, Saveetha Medical college and Hospital, India
3
Assistant Professor, Department of General Medicine, Saveetha Medical College and Hospital, India
Open Access
DOI : 10.5083/ejcm/25-05-23
Received
Feb. 18, 2025
Revised
March 15, 2025
Accepted
April 22, 2025
Published
May 7, 2025
Abstract
Background: Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a debilitating disorder characterized by extreme fatigue that is not improved with rest and worsens with physical or mental exertion. Recent studies suggest a potential role of micronutrient deficiencies, particularly Vitamin D, in the pathophysiology and symptomatology of CFS.
Objective: To assess the prevalence of Vitamin D deficiency in adults diagnosed with Chronic Fatigue Syndrome. Methods: A cross-sectional study was conducted involving 100 adult patients (aged 18–60 years) diagnosed with CFS based on CDC criteria. Serum 25-hydroxyvitamin D levels were measured, and deficiency was defined as <20 ng/mL. Demographic data, fatigue severity, and comorbidities were recorded and analyzed.
Results: Among the 100 participants, 68% were found to have Vitamin D deficiency, 22% had insufficiency (20–30 ng/mL), and only 10% had sufficient levels (>30 ng/mL). A significant association was found between Vitamin D deficiency and higher fatigue severity scores (p<0.01).
Conclusion: Vitamin D deficiency is highly prevalent among adults with Chronic Fatigue Syndrome. Screening for and correcting this deficiency may be a valuable adjunct in managing fatigue symptoms.
Keywords
Chronic Fatigue Syndrome
Vitamin D deficiency
Fatigue
Micronutrients
Research Article | Volume 15 Issue 5 (May, 2025) | Pages 120 - 124
Assessment of Vitamin D Deficiency Prevalence in Adults with Chronic Fatigue Syndrome: A Cross-Sectional Study
Pon. Saranya1
Vikrannth Vasanthakumar2
N. Deepthi3
1
Assistant Professor, Department of General Medicine, Govt Thiruvannamalai Medical College and Hospital, India
2
Associate Professor, Department of General Medicine, Saveetha Medical college and Hospital, India
3
Assistant Professor, Department of General Medicine, Saveetha Medical College and Hospital, India
Open Access
DOI : 10.5083/ejcm/25-05-23
Received
Feb. 18, 2025
Revised
March 15, 2025
Accepted
April 22, 2025
Published
May 7, 2025
Abstract
Background: Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a debilitating disorder characterized by extreme fatigue that is not improved with rest and worsens with physical or mental exertion. Recent studies suggest a potential role of micronutrient deficiencies, particularly Vitamin D, in the pathophysiology and symptomatology of CFS.
Objective: To assess the prevalence of Vitamin D deficiency in adults diagnosed with Chronic Fatigue Syndrome. Methods: A cross-sectional study was conducted involving 100 adult patients (aged 18–60 years) diagnosed with CFS based on CDC criteria. Serum 25-hydroxyvitamin D levels were measured, and deficiency was defined as <20 ng/mL. Demographic data, fatigue severity, and comorbidities were recorded and analyzed.
Results: Among the 100 participants, 68% were found to have Vitamin D deficiency, 22% had insufficiency (20–30 ng/mL), and only 10% had sufficient levels (>30 ng/mL). A significant association was found between Vitamin D deficiency and higher fatigue severity scores (p<0.01).
Conclusion: Vitamin D deficiency is highly prevalent among adults with Chronic Fatigue Syndrome. Screening for and correcting this deficiency may be a valuable adjunct in managing fatigue symptoms.
Keywords
Chronic Fatigue Syndrome
Vitamin D deficiency
Fatigue
Micronutrients