Atypical cauda equina syndrome with lower limb clonus: a literature review and case report, 2019, Mirza et al

Andy · Nov 16, 2019

Background
Cauda Equina Syndrome (CES) is a neurosurgical emergency warranting urgent surgical decompression. Treatment delay may precipitate permanent adverse neurological sequelae. CES is a clinical diagnosis, corroborated by radiological findings. Atypical presentations should be acknowledged to avoid inappropriately rejected diagnoses.

Case Description
We report the case of a young woman exhibiting bilateral lower limb weakness, perineal numbness, sphincter disturbance and lower limb clonus. Classically, CES displays LMN signs in the lower limbs. The presence of clonus, an UMN sign, brought the diagnosis into doubt. The history included chronic fatigue, difficulty mobilising and intermittent blurred vision. A lumbo-sacral MRI demonstrated a large disc prolapse at L5/S1. The cord was not low-lying or tethered. Therefore, the possibility of second diagnoses, including of inflammatory or demyelinating nature, was raised. An urgent MRI of the brain and cervicothoracic cord identified no other lesions. On balance, the clinical presentation could overwhelmingly be attributed to the L5/S1 disc prolapse. Given the time critical nature of CE compression, an urgent laminectomy and discectomy was offered with continued postoperative investigation of the clonus. Intraoperatively, significant CE compression was found. The operation proceeded uneventfully and the patient recovered fully. In the immediate postoperative period, the clonus persisted yet subsequently resolved completely.

Conclusions
We conclude that the clonus was attributable to CE compression and not a second pathology. The corresponding neuroanatomical correlate remains non-delineated. The presence of clonus does not preclude a diagnosis of CES. If the clinico-radiological information otherwise correlate, surgery should not be delayed whilst alternative diagnoses are sought. The literature is reviewed.
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Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1878875019328451
Scihub, https://sci-hub.se/10.1016/j.wneu.2019.10.198

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Atypical cauda equina syndrome with lower limb clonus: a literature review and case report, 2019, Mirza et al

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Atypical cauda equina syndrome with lower limb clonus: a literature review and case report, 2019, Mirza et al

Andy Committee Member

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