Review Beyond the acute phase: a comprehensive literature review of long-term sequelae resulting from infectious diseases 2024 Izquierdo-Condoy et al

Infectious diseases have consistently served as pivotal influences on numerous civilizations, inducing morbidity, mortality, and consequently redirecting the course of history. Their impact extends far beyond the acute phase, characterized by the majority of symptom presentations, to a multitude of adverse events and sequelae that follow viral, parasitic, fungal, or bacterial infections. In this context, myriad sequelae related to various infectious diseases have been identified, spanning short to long-term durations. Although these sequelae are known to affect thousands of individuals individually, a comprehensive evaluation of all potential long-term effects of infectious diseases has yet to be undertaken.

We present a comprehensive literature review delineating the primary sequelae attributable to major infectious diseases, categorized by systems, symptoms, and duration. This compilation serves as a crucial resource, illuminating the long-term ramifications of infectious diseases for healthcare professionals worldwide. Moreover, this review highlights the substantial burden that these sequelae impose on global health and economies, a facet often overshadowed by the predominant focus on the acute phase. Patients are frequently discharged following the resolution of the acute phase, with minimal long-term follow-up to comprehend and address potential sequelae. This emphasizes the pressing need for sustained vigilance, thorough patient monitoring, strategic health management, and rigorous research to understand and mitigate the lasting economic and health impacts of infectious diseases more fully.

Open access, https://www.frontiersin.org/articles/10.3389/fcimb.2024.1293782/full

 

Mentions Long Covid

"Despite efforts to control infectious diseases, numerous outbreaks continue to occur. The emergence of SARS-CoV-2 in Wuhan, China, in 2019 is a prime example. This caught global health systems off guard and had significant global health impacts (Johns Hopkins University, 2020). Through unprecedented efforts, the rapid development of SARS-CoV-2 vaccines has partially helped humanity to overcome the pandemic in less than two years. However, researchers worldwide have identified a range of symptoms and sequelae persisting long after the acute stage of COVID-19 has ended—so-called ‘Long-COVID.’ Currently, ‘Long-COVID’ is regarded as a new pandemic, with projections suggesting that approximately 150 million people worldwide may suffer from the condition by the end of 2022 (Izquierdo-Condoy et al., 2022a; Notarte et al., 2022)."

but no mention of ME/CFS.

 

"comprehensive"

"thousands"

Literally ignores centuries with millions of reports. Good grief the intellectual laziness.