Childhood traumatization is associated with differences in TRPA1 promoter methylation in [..] multisomatoform disorder [..], 2019, Achenbach et al

Full title: Childhood traumatization is associated with differences in TRPA1 promoter methylation in female patients with multisomatoform disorder with pain as the leading bodily symptom

Open access at https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-019-0731-0

 

Can someone translate this into simple language please?

 

So childhood trauma does not lead to more pain sensitivity but being ill does. Yet they have manage to bend these results to say that childhood trauma leads to functional somatic syndromes!

 

"We found correlation and argue that it means causation"

This table shows clear problems with any correlation with trauma, a very subjective self-assessment, since there are variations in chronic pain patients with no trauma compared to controls. The hypothesis should mean no difference and yet there is, likely down to the imprecise nature of assessing whatever people may mean by trauma. This is just fishing for some way to rationalize a predetermined belief that trauma is a significant causative factor in chronic pain.

Basically they found nothing of significance but argue they did because they want to do more research and reporting null results does not favor that. Should be referred to remedial science 101. Instead this will likely lead to more funding. Typical.

 

if you cannot dress garbage in twenty dollar words then you have no future in psychology . or baffling people with imprecise language can be great for your bank account . all this tripe just makes me ill .

 

The abstract does not even say which cells the methylation was in. I doubt they checked brain cells.

 

I don't suppose that there would be any reason to think nucleated blood cells and whatever else is floating around tell us much about relevant nervous functioning in this case.