Clinical Update | Ultra-Low-Dose Metabolically Armed CD19 CAR-T Successfully Treats First Systemic Lupus Erythematosus Patient

Jaybee00

Senior Member (Voting Rights)

The first enrolled systemic lupus erythematosus (SLE) patient achieved "medication-free DORIS remission" (complete remission without ongoing treatment) after receiving a single infusion of Meta10-19 injection at a dose of only 1‰ (one-thousandth) of the standard commercial CAR-T dose (2×106 CAR-T cell/kg). The patient discontinued all SLE-related medications following clinical assessment.
 
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