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Anyone can do post-publication peer review.
Anyone can be a steward of the scientific literature.
Anyone can do forensic metascience.
Anyone can sleuth.
However, investigating the integrity of the published scientific literature often requires domain-specific knowledge that not everyone will have. This open source project is a collection of guides written and maintained by publication integrity experts to distribute this domain-specific knowledge so that others can participate in post-publication peer review.
COSIG currently hosts 27 guides and was last updated on 4 June 2025. Guides can be downloaded as individual PDFs. A combined PDF with all guides included can be downloaded here.
Suggestions to improve COSIG can be submitted by opening an issue on COSIG's GitHub repo or by emailing admin@cosig.net. Before contributing, read COSIG's Contributing and Code of Conduct pages.
---------
Anyone can do post-publication peer review.
Anyone can be a steward of the scientific literature.
Anyone can do forensic metascience.
Anyone can sleuth.
However, investigating the integrity of the published scientific literature often requires domain-specific knowledge that not everyone will have. This open source project is a collection of guides written and maintained by publication integrity experts to distribute this domain-specific knowledge so that others can participate in post-publication peer review.
COSIG currently hosts 27 guides and was last updated on 4 June 2025. Guides can be downloaded as individual PDFs. A combined PDF with all guides included can be downloaded here.
Suggestions to improve COSIG can be submitted by opening an issue on COSIG's GitHub repo or by emailing admin@cosig.net. Before contributing, read COSIG's Contributing and Code of Conduct pages.
Table of Contents
General Guides- PubPeer commenting best practices
- Extracting vector graphics from a PDF
- The vertical line test
- Image duplication
- Image compression artifacts
- Software for image forensics
- Reporting publication integrity issues to publishers
- Citations
- Citations to retracted publications
- Formulaic research
- Plagiarism of text
- Common dismissive responses to integrity concerns
- Suspicious venues
- Ethical approval of human subjects research
- Antibody validation
- Misidentified and non-verifiable cell lines
- Nucleotide sequence reagents
- Tumor burden
- X-ray diffraction patterns - Scherrer's equation
- X-ray diffraction patterns - data duplication
- Energy dispersive X-ray spectroscopy
- Elemental composition
- Tauc plots