Preprint COVID-19 Reproduction Numbers and Long COVID Prevalences in California State Prisons, 2024, Worden et al.

Discussion in 'Long Covid research' started by SNT Gatchaman, Dec 18, 2024.

  1. SNT Gatchaman

    SNT Gatchaman Senior Member (Voting Rights)

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    COVID-19 Reproduction Numbers and Long COVID Prevalences in California State Prisons
    Lee Worden; Rae Wannier; Helena Archer; Seth Blumberg; Ada T Kwan; David Sears; Travis C Porco

    Prisons have been hotspots for COVID-19 and likely an important driver of racial disparity in disease burden. From the first COVID-19 case detected through March 25, 2022, 66,684 of 196,652 residents of California's state prison system were infected, most of them in two large winter waves of outbreaks that reached all 35 of the state prisons.

    We used individual-level data on disease timing and nightly room assignments in these prisons to reconstruct locations and pathways of transmission statistically, and from that estimated reproduction numbers, locations of unobserved infection events, and the subsequent magnitude and distribution of long COVID prevalence.

    Where earlier work has recommended smaller cells over large dormitory housing to reduce transmission, recommended use of cells with solid doors over those with bars only, and cautioned against reliance on solid doors (e.g., in cold months when HVAC systems can circulate aerosols), we found evidence of substantial transmission in both dorms and cells regardless of the door and season. Effective reproduction numbers were found to range largely between 0 and 5, in both cells and dorms of all door types. Our estimates of excess case rates suggest that as a result of disparities in incarceration, prison outbreaks contributed to disproportionate disease burden on Black and Indigenous people in California.

    We estimated that 9,100-11,000 people have developed long COVID as a result of infection in these prison outbreaks, 1,700-2,000 of them with disabling consequences, and that this burden is disproportionately on Black and Indigenous people in comparison to the state as a whole.

    We urge high-quality medical care for prison residents affected by long COVID, and decarceration to reduce the risk of future outbreaks of both COVID-19 and other diseases.

    Link | PDF (Preprint: MedRxiv) [Open Access]
     
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  2. SNT Gatchaman

    SNT Gatchaman Senior Member (Voting Rights)

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    (Close to nominative determinism with the first author)
     
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  3. Yann04

    Yann04 Senior Member (Voting Rights)

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    I shudder to think what would happen to a very severe person in a carceral system like america’s.

    I imagine it would be interpreted as maligering and treated as such until the person inevitably dies from not being able to pace and feed themselves properly.
     
  4. Yann04

    Yann04 Senior Member (Voting Rights)

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    I like to think that was their reasoning behind giving that person first authorship.
     
  5. forestglip

    forestglip Senior Member (Voting Rights)

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    That's interesting. They all have a very similar environment, presumably including similar diet and exercise, in prison, so I wonder if it's due to environment before they entered or genetics.

    Edit: Oh I misread, the abstract isn't saying they have a higher incidence in prison than others, it's comparing to outside prison.

    So maybe the prison ratio is a bit closer to the "true" ratio if you were able to control for environment.
     
    Last edited: Dec 18, 2024
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