CRS plus HIPEC in Mesothelioma Patient with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2023, Spiliotis

Case report from Greece

CRS* plus HIPEC** in Mesothelioma Patient with Myalgic Encephalomyelitis /Chronic Fatigue Syndrome (ME/CFS)

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*Cytoreductive Surgery
**Hyperthermic Intraperitoneal Chemotherapy

Conclusion
In conclusion our case is the first reported in literature in which patients with MF/CFS are supported after cytoreductive surgery and Hipec with successful outcome.
• The insurance of magnesium and potassium levels are adequate,
• Hydrate the patients prior to and after surgery,
• Use catecholamines, sympathomimetics, vasodilators, and hypotensive agents with caution,
• Avoid histamine-releasing anesthetic and muscle-relaxing agents, if possible,
• Use sedating drugs sparingly,
• Ask about herbs and supplements, and advise patients to taper off such therapies at least one week before surgery,
• Consider cortisol supplementation in patients who are chronically on steroid medications or who are seriously ill.