Since transthyretin is a transport protein for thyroid hormone (thyroxine aka T4) and retinol (vitamin A) I wonder what effect, if any, being hypothyroid or hyperthyroid has, whether "subclinical" or overt. And whether low or high levels of vitamin A have any impact.
Also what effect does clearing the transthyretin amyloid plaque with autoantibodies have on thyroid function and eyesight?