Review Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2023, Grach et al

Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic neurologic disease often preceded by infection. There has been increased interest in ME/CFS recently because of its significant overlap with the post-COVID syndrome (long COVID or post-acute sequelae of COVID), with several studies estimating that half of patients with post-COVID syndrome fulfill ME/CFS criteria. Our concise review describes a generalist approach to ME/CFS, including diagnosis, evaluation, and management strategies.

Open access: https://www.mayoclinicproceedings.org/article/S0025-6196(23)00402-0/fulltext

 

Not too bad but the opening sentence isn't supported.

Referencing Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An IOM Report on Redefining an Illness (2015, JAMA) which is a viewpoint article written by the IOM chair in JAMA rather than the IOM report itself.

 

Referencing Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An IOM Report on Redefining an Illness (2015, JAMA) which is a viewpoint article written by the IOM chair in JAMA rather than the IOM report itself.

In medical terminology, can the Central nervous system also be referred to as a multisystem, such as Multiple system atrophy?

I’m thinking multisystem is another term for the CNS.

 

Sharing from Jaime Seltzer, one of the co-authors from #MEAction.

https://twitter.com/exceedherg.../status/1711197702564856010

Per Jaime, "It’s in the top <1% most shared of all Mayo Clinic publications. It’s the most shared paper amongst its contemporaries at Mayo Clinic Proceedings. It’s in the top 0.2% most shared research products of all time. It’s been live less than a week."

 

I think that MSA implies multiple neurological systems, as opposed to a single neurological system. The disease definition involves autonomic dysfunction with either Parkinsonian or cerebellar symptoms and was derived to wrap previously individually named conditions. See Second consensus statement on the diagnosis of multiple system atrophy (2008, Neurology). So it looks as if "multiple system" is being used to reference CNS and ANS (the latter having both central and peripheral components - preganglionic/postganglionic).

In contrast, the IOM report advocated renaming to "systemic exertion intolerance disease", where systemic is multi organ systems, encompassing eg cardiovascular, musculoskeletal, neurological, endocrine etc.

 

I wanted to share it but decided not to when I read the recommendations.

 

I thought the figure on PEM was helpful.



For anyone who wants to post this image on social media, here's an image description I wrote that you can add as alt text (the text read by screen readers or that is shown if the image fails to load) when you post the image:

Image descriptions take work so I wanted to share just in case it's helpful for someone out there.

EDIT: And right after I posted I noticed several typos! Fixing now, let me know if you see errors/typos.

 

6-minute video:
Description: Dr. Stephanie Grach, an Assistant Professor of Medicine in the Division of General Internal Medicine at Mayo Clinic in Rochester, MN, and Jaime Seltzer, Director of Scientific and Medical Outreach at #MEAction and a researcher with Stanford School of
Medicine in Palo Alto, CA, share insights from their Concise Review on the diagnosis and management of myalgic encephalomyelitis / chronic fatigue syndrome, also known as “ME/CFS.” They note infection-associated chronic illness is an up-and-coming area of
research and state it is vital that medical providers learn more about how to recognize and address this disease. The Concise Review will be appearing in the October 2023 issue of Mayo Clinic Proceedings.
Available at: https://mayocl.in/3L8Olwb

https://www.youtube.com/watch?v=WZLY3nU0LbY

There is also a transcript at the link

 

#MEAction sent out email with some stats about how much this document has been downloaded, see this post:

https://www.s4me.info/threads/usa-news-from-meaction.19675/page-6#post-498549