Drug may counteract muscle loss and osteoporosis after rapid weight loss, 2025

Weight loss medication has taken the world by storm and helped many overweight people. But for some, significant weight loss also comes with a loss of muscle mass and can lead to an increased risk of osteoporosis.

New research now suggests that the drug, bimagrumab, may be able to alleviate some of this risk, says PhD student Frederik Duch Bromer and postdoc Andreas Lodberg from the Department of Biomedicine at Aarhus University, who are behind the study.

"We are the first to study how certain drugs affect bones, and the results show that bimagrumab can increase the amount of bone tissue while building muscle mass, and this could be very important for the many people currently taking weight loss medication."

Bimagrumab was originally developed to treat muscle loss and dysfunction, but since then, it has become apparent that it also has a fat “burning” component to it. So, if approved, it could be part of a second-generation weight loss drug on the market.
LINK