https://www.endotext.org/wp-content/uploads/pdfs/chronic-fatigue-syndrome.pdf CHRONIC FATIGUE SYNDROME WT Lim, Endocrine and Metabolic Unit, Royal Adelaide Hospital, North Terrace, Adelaide SA 5000. Alexlim.1992@gmail.com DJ Torpy, MBBS, PhD, FRACP, Endocrinologist, Endocrine and Metabolic Unit, Royal Adelaide Hospital, North Terrace, Adelaide SA 5000. David.torpy@sa.gov.au Updated August 14, 2023 ABSTRACT Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an enigmatic medical condition that has growing prevalence across the globe, often diagnosed after exclusion of other medical or mental illnesses. As there is no clinical test to confirm the presence of this condition, the diagnosis is syndromic based on different clinical definitions. There was mixed evidence to support the use of a specific therapy that provides palliative effect. Pathophysiological hypotheses can be categorized into infection, immune, mitochondrial, neurobehavioral, or stress system (HPA axis and sympathetic nervous system) disorders. The prognosis of ME/CFS is mixed but recovery does occur in many cases, over time. All-cause mortality rate is not increased.
https://www.endotext.org/ Endotext.org is a non-profit web-based source of trustworthy information on endocrine disease written for physicians around the world. It is a comprehensive, authoritative, regularly up-dated, un-biased, and free, on-line textbook directed to physicians, trainees, students, and other health professionals. Our chapters cover the broad area of Clinical Endocrinology, emphasizing clinical endocrine practice, including the most current information on the manifestations of endocrine diseases, diagnoses, and treatments. Endotext.org is the premier provider of peer-reviewed endocrine information on the Web, and we invite your critical comparison to any Endocrinology source available anywhere in the world. ENDOTEXT is republished by NIH/NLM/NCBI Books, and all chapters are indexed on PUBMED. It is organized by the Editor Kenneth Feingold, MD, 28 Section Editors, and over 400 Authors. All html material may be freely downloaded for personal use and teaching. A PDF version of each chapter can also be downloaded for a small one-time fee ($5) or for an unlimited times (for any chapter) over a year ($20). There are more than 70,000 registered users. Endotext is owned by MDText, a non-profit organization registered in Oregon (USA), and contributions are Federal Tax-exempt as a public charity under IRC Section 509(a)(2). Endotext.org is solely responsible for all content. James DelGrande is our Web Administrator. Our site is made available largely through the generosity of the authors and editors who have provided their work as a service to the profession.
That's a bit of a depressing read. It sort of gets some things right, but not quite. As you would expect from a resource for endocrinologists, there is a big emphasis on issues to do with cortisol and the HPA axis. It would be possible to address the many issues in this resource, but it would take quite a while and there's no guarantee that ENDOTEXT would be interested in engaging. I guess a question is, 'how influential is ENDOTEXT'? Maybe it would be more productive and useful to publish a good review of the evidence around cortisol in ME/CFS.
Cognitive behavioral therapy involves the provision of information and counselling to reduce the psychological impediments to recovery, as well as encouraging the patient to participate at an appropriate level of social and occupational activity. Because we are such incompetent fools with no idea how to engage in "an appropriate level of social and occupational activity" that we need to be 'trained' by experts who have no idea what they are dealing with nor how to deal with it.
I constantly wonder what the motivation is for doctors to write reviews about things they do not know much about.
I hope for someone's sake that the text you quoted was written by a LLM because even then it would have to be a pretty bad one and that's just embarrassing. Reads like someone imitating human language and failing badly at it.