Factors associated with quality of life in long-COVID syndrome, 2025, Artemiadis et al

Abstract:

Approximately 10% of patients experience persistent symptoms following COVID-19, known as long-COVID syndrome. This cross-sectional study explored factors of quality of life (QoL) in 53 long-COVID patients.

QoL was measured using the World Health Organization-Five Well-Being Index, fatigue with the Fatigue Visual Analogue Scale, and psychological health with the Depression-Anxiety-Stress-21 questionnaire. Six neuropsychological tests assessed information processing speed, verbal memory, visual memory, working memory, attention, language, fluency, recall, and visuospatial function with a composite score calculated by averaging zscores.

Patients (76% female, mean age: 54.1 years) were assessed 8.7 months postinfection. Cognitive impairment, present in 49% of the sample, was not associated with QoL. In multiple linear regression, gender, fatigue, and psychological distress accounted for 42% of QoL variance, with fatigue and distress contributing 7% and 11%, respectively.

Further studies are needed to determine if fatigue and psychological distress are causally related to QoL in long-COVID and could be treatment targets.

LINK (Paywall)

 

Someone really has to put a stop to this mad questionnaire industry. It's like fishing for cherries, but so much worse. They serve absolutely no useful purpose in real life.

 

They find what they are looking for, its a self fulfilling prophecy.

 

Am I reading this right?
Fatigue 7%, distress 11%. And the other "symptom" being female accounts for the rest of 42 %?
Can someone help this poor foreigner make sense of this?

 

Yeah you’re getting it right, they seem to have found that the “female” variable induced a 24% difference in severity. (Assuming that’s an increase, but unsure by the abstract).