Dolphin
Senior Member (Voting Rights)

Functional medicine approaches to energy metabolism: chronic fatigue syndrome, brain-gut axis and weight control
Chronic fatigue syndrome; Mitochondrial dysfunction; Micronutrients; Brain-gut axis
J Korean Inst Funct Med. 2025 May;8(1):103-111. 10.32581/jkifm.2025.8.1.103.
Functional medicine approaches to energy metabolism: chronic fatigue syndrome, brain-gut axis and weight control
Affiliations- 1Morningwalk Clinic, Seoul, Korea
- 2Refrery Sarang Clinic, Suwon, Korea
- KMID: 2568804
- DOI: http://doi.org/10.32581/jkifm.2025.8.1.103
Abstract
Chronic fatigue syndrome is a long-term condition that can affect different parts of the body which includes symptoms of extreme tiredness which can make daily activities difficult, sleep problems, brain fog.The symptom “chronic fatigue” might seem like a simple physical status; however, it might be a crucial sign of mitochondria dysfunction, problematic neurotransmitter synthesis, increased micro-inflammation and/or increased gut permeability.
These metabolic conditions are likely to cause lethal vascular diseases, neurological deficits, psychological disorders or serious immune reactions if patients do not receive proper care.
Thorough clinical approaches and individualized treatments should be achieved not only to resolve symptoms but also to maintain healthy status.
Functional medicine approach from simple blood analysis to urine organic acid analysis and food IgG4 antibody test and treatment methods which help to recover mitochondrial function could be proper options.