Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies, 2022, Yang et al

Discussion in 'ME/CFS research' started by Andy, Feb 23, 2022.

  1. Andy

    Andy Committee Member

    Messages:
    23,036
    Location:
    Hampshire, UK
    Abstract

    Background

    Chronic fatigue syndrome (CFS) is a complex and often disabling chronic condition emerging worldwide, with no curative or definitive therapy yet identified. Ginseng has been widely used to treat fatigue in other patient groups and conditions; however, a systematic review focusing solely on the impact of ginseng on fatigue in patients with CFS has not been performed.

    Objective
    This study aimed to assess the current state of evidence regarding ginseng for CFS.

    Methods
    Multiple databases were searched from inception to October 2020. All data was extracted independently and in duplicates. Outcomes of interest included the effectiveness and safety of ginseng in patients with CFS.

    Results
    2 studies enrolling 68 patients were deemed eligible, including one randomized clinical trial and one prospective observational study. The certainty of evidence in the effectiveness outcome was low and moderate from both studies, while the safety evidence was very low as reported from one study.

    Conclusion
    Study findings highlight a potential benefit of ginseng therapy in the treatment of CFS. However, we are not able to draw firm conclusions due to limited clinical studies. The paucity of data warrants limited confidence. There is a need for future rigorous studies to provide further evidence.

    Open access, https://journals.sagepub.com/doi/10.1177/2164957X221079790
     
  2. Shadrach Loom

    Shadrach Loom Senior Member (Voting Rights)

    Messages:
    1,053
    Location:
    London, UK
    It wouldn’t affect the value of this research much if they omitted the seng and just speculated about gin.
     
    MEMarge, Hutan, TigerLilea and 6 others like this.
  3. Trish

    Trish Moderator Staff Member

    Messages:
    55,433
    Location:
    UK
    What is the point of doing a systematic review that includes only one clinical trial?
     
  4. Jaybee00

    Jaybee00 Senior Member (Voting Rights)

    Messages:
    2,180
    The point was for the authors to generate a publication that they can use on their tenure and promotion application.

    ETA—they are from Mayo Clinic.
     
    MEMarge, Hutan, MSEsperanza and 6 others like this.
  5. Jaybee00

    Jaybee00 Senior Member (Voting Rights)

    Messages:
    2,180
    @dave30th Dont you have a contact at Mayo? Maybe you can make an inquiry why they thought it was important to involve the time of SEVEN researchers to review ONE clinical study. This is ridiculous!
     
  6. MSEsperanza

    MSEsperanza Senior Member (Voting Rights)

    Messages:
    2,947
    Location:
    betwixt and between
    Last edited: Mar 29, 2022
    Peter Trewhitt likes this.
  7. NelliePledge

    NelliePledge Moderator Staff Member

    Messages:
    14,865
    Location:
    UK West Midlands
    Odd they don’t include his final words.

    i doubt it
     
    Trish, MSEsperanza and Wonko like this.
  8. Hutan

    Hutan Moderator Staff Member

    Messages:
    29,383
    Location:
    Aotearoa New Zealand
    We have a treatment thread on Ginseng here: Ginseng
     
    Peter Trewhitt and Trish like this.

Share This Page