Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function, 2019, Blau et al

Maybe this could be part of our muscle fatiguability?

www.cell.com/cell-reports/fulltext/S2211-1247(19)30731-4

 

Nice find Andy. Not sure if you know that Helen Blau is among the top muscle biologists in the world. This work is on muscle stem cells (previously known as satellite cells) in rodents. These stem cells are usually quiescent in adult muscle because muscle fibers are post-mitotic (fully differentiated, do not proliferate). The role of muscle stem cells in humans is not clear except with focal injury.

 

Thanks.

I'm afraid I'm someone with no biology/medical training of any sort but daily emails that highlight new papers that match certain keywords, and from there I guess what might be useful/interesting. I rely on the members with brains to pick up on anything worthwhile.

 

Where do these emails come from? Is it a computer algorithm that picks up new papers on PubMed etc?

 

Yes, exactly that. You can sign up https://www.storkapp.me/

A bit of background to it, http://www.alivelearn.net/?p=1798

 

Thanks @Andy I have set everything up, will see if it works tomorrow.

 

A brief glance suggests that this paper has similarities with Neil McGregor's talk at the EMERGE conference.

I have just read thro' Cort's summary from HR produced on 15 June 2019. It mentions histone acetylation alongside the problems of glycolysis etc.