Going long: Viruses linger with lasting impact

Sly Saint

Senior Member (Voting Rights)
By Diane Mapes, Fred Hutch Cancer center

Some viruses, like the common cold, are a flash in the pan. They infect us, our bodies fight back — which is what makes us sick — and then they’re gone, until the next variant rolls along.

Other viruses linger.

Once HIV gains a foothold in a person’s body it never leaves, except for the few individuals who’ve been cured by bone marrow transplant; people with HIV must continually take antiretroviral drugs to stay healthy and not develop AIDS.

HSV1 and 2 — the viruses responsible for genital herpes and cold sores — flare and fade throughout a person’s life. And another herpes virus, varicella-zoster, first presents as chickenpox, then hides for years, even decades, until it reactivates as shingles. Human papilloma virus, or HPV, can trigger cervical, head and neck, anal, vulvar and other cancers. And norovirus recently was identified as a potential driver of Crohn’s disease.

From Epstein-Barr to Zika, the list of virus-associated chronic ailments goes on.

Millions of Americans infected by the new coronavirus, SARS-CoV-2, are now dealing with its post-acute sequelae, or PASC, mostly known as long COVID, the latest long-term condition to stem from a virus.

We know they’re common; we know they’re annoying, and we know that when it comes to the immunocompromised or the unlucky, they can be deadly. But three years after COVID-19 rocked the world, are we now learning viruses are more of a threat than we imagined? Do they all “go long”?

very long piece

https://www.fredhutch.org/en/news/c...th-lasting-impact-hpv-hsv-hiv-long-covid.html
 
But three years after COVID-19 rocked the world, are we now learning viruses are more of a threat than we imagined? Do they all “go long”?

How many people have the good grace to acknowledge much has been known about long term impacts of viruses, but much of the science and medical community declined to take these effects serious, particularly in relation to ME? How many people will acknowledge the ME/CFS community desperately tried to warn of the potential impact of what is now called Long Covid, with in the region of 50% of Long Covid suffers being now found to meet the diagnostic criteria for ME/CFS? How many will acknowledge the lost research opportunities if research had been begun at the start of the pandemic to try to identify who subsequently developed Long Covid based on cohorts first assessed pre infection with Covid-19 as suggested by many in the ME community?

It is not that this was unexpected to anyone with knowledge of ME/CFS, particularly given other SARS viruses seemed to elicited comparatively higher levels of ME/CFS in relation to many other viruses.

That an individual or indeed many individuals is/are surprised by something does not mean it is inherently surprising.
 
Back
Top Bottom