Preprint Improving Quality of Life in Chronic Fatigue Syndrome using Antioxidant Complex Twendee M®., 2024, You

Discussion in 'ME/CFS research' started by Dolphin, Feb 8, 2024.

  1. Dolphin

    Dolphin Senior Member (Voting Rights)

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    https://www.preprints.org/manuscript/202402.0373/v1

    Preprint Article Version 1
    Improving Quality of Life in Chronic Fatigue Syndrome using Antioxidant Complex Twendee M®.
    Fukka You
    ,
    Yoshiaki Harakawa
    ,
    Toshikazu Yoshikawa
    ,
    Haruhiko Inufusa
    *

    Version 1 : Received: 29 January 2024 / Approved: 6 February 2024 / Online: 6 February 2024 (11:06:29 CET)

    How to cite: You, F.; Harakawa, Y.; Yoshikawa, T.; Inufusa, H. Improving Quality of Life in Chronic Fatigue Syndrome using Antioxidant Complex Twendee M®.. Preprints 2024, 2024020373. https://doi.org/10.20944/preprints202402.0373.v1

    Abstract

    Chronic fatigue syndrome (CFS) is a disease in which fatigue that interferes with daily life persists for six months or longer.

    The number of patients with CFS is increasing, as CFS-like symptoms have been reported to occur in the sequelae of both COVID-19 infection and the SARS-CoV-2 vaccine, both of which have become significant issues in recent years.

    While the pathogenesis mechanism is not yet fully understood, research suggests that oxidative stress (OS) may play a role in the development of CFS.

    In this paper, we discuss the antioxidant potential of the antioxidant formulation Twendee M® (TwM) and the results of a questionnaire that monitored changes in symptoms before and after TwM in a total of 23 men and women diagnosed with CFS.

    TwM is a supplement containing 15 different ingredients, and has a strong antioxidant capacity that cannot be achieved with a single antioxidant ingredient.

    The results of the questionnaire showed that TwM significantly improved all of the major symptoms of CFS, including fatigue, muscle pain, joint pain, sleep disturbance, decreased memory and concentration, and headache.

    TwM was shown to alleviate various symptoms of CFS and improve quality of life.

    Keywords

    oxidative stress; Twendee M®; antioxidant; chronic fatigue syndrome; ROS; mitochondria; inflammation

    Subject

    Biology and Life Sciences, Life Sciences
     
  2. Trish

    Trish Moderator Staff Member

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    Location:
    UK
    That abstract reads more like a marketing advertisement than a scientific abstract.
     
  3. Trish

    Trish Moderator Staff Member

    Messages:
    55,446
    Location:
    UK
    As I thought, it's more like market research than scientific research. Funded by the company that markets the supplement. 23 people recruited online filled in questionnaires on a website before and after taking the supplement for 2 months. Subjective outcomes, no control group.
     
    EndME, alktipping, Ash and 3 others like this.
  4. Creekside

    Creekside Senior Member (Voting Rights)

    Messages:
    1,221
    I'm sure they could have gotten similar results for any treatment, including magic crystals and Neanderthal Healing Chants (verified as genuine by experts!!!)
     

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