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In Search of Effective Treatments for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2019, Theoharides

Discussion in 'ME/CFS research news' started by Andy, May 4, 2019.

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  1. Andy

    Andy Committee Member

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    Short article, looks to be some kind of foreword to an ME focused edition of the journal.
    Open access at https://www.clinicaltherapeutics.com/article/S0149-2918(19)30175-4/fulltext
     
    Andy, May 4, 2019
    #1
    Esther12, ladycatlover and Inara like this.
  2. Trish

    Trish Moderator Staff Member

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    It looks like this is introducing the second collection of articles, following the ones he introduced with this article:
    A Timely Multidisciplinary Update on ME/CFS (link to thread).

    I am puzzled by his definitions of ME/CFS.
    In the first article he says:
    And now in this article he says:
     
    Trish, May 4, 2019
    #2
    rvallee, adambeyoncelowe and Andy like this.
  3. Wonko

    Wonko Senior Member (Voting Rights)

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    My exhaustion is easily explained by the following;

    I am alive,
    I have ME.

    I would imagine, but as I'm not an 'expert' I cannot be totally sure, that resolving either one would resolve my exhaustion.

    Possibly a subject for research.
     
    Wonko, May 4, 2019
    #3
    Kitty, Trish and adambeyoncelowe like this.
  4. Mithriel

    Mithriel Senior Member (Voting Rights)

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    "characterized primarily by severe, unexplained fatigue"

    I am in a bit of a relapse so I am feeling bored and grumpy but I am getting angrier and angrier about people who should know better describing our disease this way.

    It is an ABNORMAL RESPONSE TO EXERCISE which characterises ME. :banghead::banghead::banghead: This can lead to experiencing fatigue most of the time because every bit of exertion causes payback but GET IT RIGHT!
     
    Mithriel, May 4, 2019
    #4
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  5. Wonko

    Wonko Senior Member (Voting Rights)

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    Grumpiness would definitely appear to be a symptom of ME, unfortunately it's specificity seems low, with at least one other condition having the same symptom (VMS - Victor Meldrew Syndrome - risk factors for this appear to be being male and above a certain age - not things that typically define PwME well).

    So the diagnostic and predictive characteristics of grumpiness lead me to believe that it would probably be unsuitable as a primary sign.
     
    Wonko, May 4, 2019
    #5
    Mithriel, Peter Trewhitt, pteropus and 2 others like this.

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