Prilosec Why is this statement significant for patients with Lewy Body Disease? (LBD) Because this OTC signals the brain to turn off the proton pump in the stomach. Apparently for LBD patients, changing brain signals pushes the patients into the disease. My sister related this information to me. She would attend an LBD support group for my mother. And this information from LBDA.org: Dementia and antacids linked Widely Used Heartburn Drugs Tied to Dementia Risk Setting the record straight: PPIs do not cause Dementia And, because LBD is often misdiagnosed as Alzheimer's or just "dementia", I suspect this only happens with LBD patients. Again, it does not cause LBD but impacts and accelerates it.