LiveScience article: Strange, two-faced brain cells confirmed to exist, and they may play a role in schizophrenia

Discussion in 'Other health news and research' started by Ravn, Aug 4, 2023.

  1. Ravn

    Ravn Senior Member (Voting Rights)

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    Don't know if this could have any relevance for ME [eta: or, more likely, FND] but posting because
    a) it demonstrates how little we know about the brain, or anything really (after yesterday stumbling across another paper where they found 10,000 - yes, ten thousand - previously unknown viruses in baby faeces), and
    b) it may be of interest to members with autism or schizophrenia.
    https://www.livescience.com/health/...ist-and-they-may-play-a-role-in-schizophrenia

    Refers to this extremely technical paper (open access but haven't read)

    Anatomical and molecular characterization of parvalbumin-cholecystokinin co-expressing inhibitory interneurons: implications for neuropsychiatric conditions, 2023, Grieco et al

    https://www.nature.com/articles/s41380-023-02153-5
     
    Last edited: Aug 5, 2023
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  2. RedFox

    RedFox Senior Member (Voting Rights)

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  3. CRG

    CRG Senior Member (Voting Rights)

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    Caveat - In Mice !

    "We find that CCK&Dlx5/6 driven expression overlaps heavily with PV expression in GABAergic interneurons in mouse hippocampus and neocortex. We extend this finding to monkey hippocampus and find PV/CCK co-expression. For most of our subsequent work, we focus on the mouse hippocampus because of our extensive prior work there and because of its regular anatomical and neuronal structure."
     
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  4. Ravn

    Ravn Senior Member (Voting Rights)

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    ...and men
     
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