Low CD3+CD8+CD57+ ? Senescent T8 cells?

Hello all,


I have recently done a lymphocite panel that included CD3+CD8+ CD57+, among other things. It is very low, in my case. I did that panel again after a few months and the result was confirmed.



Oct 2019

CD3+CD8+ CD57+ 17 /mmc [170 - 375]

July 2020

CD3+CD8+ CD57+ 23 /mmc [170 - 375]



I am struggling to interpret this. Apparently these are senescent T8 cells. I have found surprisingly little information on these. They seem to be increased in a variety of infectious, autoimmune, oncological diseases, but i have not found a single instance where they would be decreased, or what it may mean. Does anybody have a clue?

 

@Jonathan Edwards best man to ask this